Results 61 to 70 of about 867,676 (291)

The Effect of Distractions on Task Performance and Enjoyment as Moderated by Regulatory Fit [PDF]

open access: yes, 2015
Every day, distractions keep people from maintaining focus and productivity. Music, in particular, is a distraction that can easily disrupt individuals mentally and physically.
Leung, Kimberly
core   +1 more source

Fear-avoidance model of chronic pain the next generation [PDF]

open access: yes, 2012
Objective: The fear-avoidance (FA) model of chronic pain describes how individuals experiencing acute pain may become trapped into a vicious circle of chronic disability and suffering.
Crombez, Geert   +4 more
core   +2 more sources

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Reverse engineering the gap gene network of Drosophila melanogaster. [PDF]

open access: yesPLoS Computational Biology, 2006
A fundamental problem in functional genomics is to determine the structure and dynamics of genetic networks based on expression data. We describe a new strategy for solving this problem and apply it to recently published data on early Drosophila ...
Theodore J Perkins   +3 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Using regulatory fit theory to examine how the communication context of compliance-gaining interactions influences compliance

open access: yesSocial Influence, 2017
Compliance-gaining research focuses mainly on how message variations differentially affect compliance; however, few studies have examined how framing the compliance-gaining goal (i.e., promotion/prevention) and providing a means to achieve the goal ...
Allison Z. Shaw   +4 more
doaj   +1 more source

The role of job satisfaction in the person-organization fit relationship in terms of goal pursuit strategies, and mental health

open access: yesMedycyna Pracy, 2014
Background: Person-organization (P–O) fit is a predictor of job satisfaction, and a misfit is a potential stressor. We aimed to examine the consequences of fit between a person and an organization in terms of goal-pursuit strategies.
Marta Roczniewska, Sylwiusz Retowski
doaj   +1 more source

bHLH Ib transcription factors regulate the transcription of FIT in Arabidopsis thaliana

open access: yesGuangxi Zhiwu, 2023
FIT (FER-LIKE IRON DEFICIENCY-INDUCED TRANSCRIPTION FACTOR) is a key regulator of Fe homeostasis in Arabidopsis, which is upregulated under Fe deficiency condition, however, the underlying regulatory mechanism is still unclear.
Yujie YANG, Gang LIANG
doaj   +1 more source

Follow the leader or the pack? Regulatory focus and academic entrepreneurial intentions [PDF]

open access: yes, 2016
Drawing on the academic entrepreneurship and regulatory focus theory literature, and applying a multilevel per- spective, this paper examines why university academics intend to engage in formal (spin-off or start-up companies and licensing university ...
Johnson, Mark   +2 more
core   +7 more sources

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

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