Results 91 to 100 of about 814,272 (323)

Diagnosis and Management of Prenatal Hereditary Pyropoikilocytosis

Prenatal Diagnosis, EarlyView.
ABSTRACT Hereditary pyropoikilocytosis (HPP) is a severe hemolytic anemia caused by variants in SPTA1, SPTB, and EPB41. These weaken horizontal interactions in the erythrocyte cytoskeleton, causing membrane fragmentation and splenic sequestration. It will readily cause fetal anemia and often hydrops fetalis. Prenatal diagnosis requires first ruling out
Connor Hartzell, Samantha Stover, Nora Gibson, Timothy Olson, James Connelly, Matthew Grace, Jennifer Andrews   +6 more
wiley   +1 more source

Anesthetic management in pregnant women with Fontan circulation: a case series

JA Clinical Reports
Background Given the advances in medicine, women with Fontan circulation are now reaching childbearing age. However, data on the mode of delivery and anesthetic management of these patients are limited.
Ai Fujita, Kazuhiro Shirozu, Midoriko Higashi, Ken Yamaura   +3 more
doaj   +1 more source

Circulating miRNA in functional tricuspid regurgitation. Unveiling novel links to heart failure: A pilot study

ESC Heart Failure
AbstractAimSevere functional tricuspid regurgitation (FTR) is associated with high risk of cardiovascular events, particularly heart failure (HF) and mortality. MicroRNAs (miRNAs) have been recently identified as novel biomarkers in different cardiovascular conditions, but no studies have focused on FTR.
Rocio Hinojar, Rafael Moreno‐Gómez‐Toledano, Elisa Conde, Ariana Gonzalez‐Gomez, Ana García‐Martin, Paz González‐Portilla, Covadonga Fernández‐Golfín, Maria Laura García‐Bermejo, Carlos Zaragoza, Jose Luis Zamorano   +9 more
openaire   +3 more sources

A coupled mitral valve -- left ventricle model with fluid-structure interaction

, 2017
Understanding the interaction between the valves and walls of the heart is important in assessing and subsequently treating heart dysfunction. With advancements in cardiac imaging, nonlinear mechanics and computational techniques, it is now possible to ...
Brown, André EX, Ch'ng, Quee-Lim, Currie, Michael, Grundy, Laura J, Hokanson, Jim, Javer, Avelino, Kerr, Rex, Lee, Chee Wai, Li, Chris, Li, Kezhi, Schafer, William R, Yemini, Eviatar   +11 more
core   +3 more sources

Fetal Diagnosis of Hypoplastic Left Heart Syndrome With Restrictive Atrial Septum—Atrial Septal Morphology, Associated Lung Disease and Outcomes

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective Fetuses with hypoplastic left heart syndrome (HLHS) and restrictive/intact atrial septum (RAS) have high mortality, partly due to pulmonary lymphangiectasia (PL). This study aimed to characterize atrial septal morphology in fetuses with HLHS and RAS and evaluate the impact of fetal intervention on PL and outcomes.
Sofie Dannesbo, Gloria Ho, Mike Seed, Vitor Guerra, Rajiv Chaturvedi, Andrew C. Cook, Niels Vejlstrup, Kasper Iversen, Henning Bundgaard, Lindsay R. Freud   +9 more
wiley   +1 more source

HLA class II associations with rheumatic heart disease among clinically homogeneous patients in children in Latvia [PDF]

, 2003
Genetic control of immune reactions has a major role in the development of rheumatic heart disease (RHD) and differs between patients with rheumatic fever (RF).
Eglite, Jelena, Gardovska, Dace, Shantere, Ruta, Sochnevs, Arturs, Stanevicha, Valda, Zavadska, Dace   +5 more
core   +2 more sources

Matsupexole: A novel nonergot dopamine receptor agonist with sustained efficacy in a rat model of Parkinson's disease and limited off‐target activity

British Journal of Pharmacology, EarlyView.
Background and Purpose Dopamine receptor agonists, particularly targeting the dopamine D2L receptor (D2LR), have been used to treat Parkinson's disease (PD). However, valvular heart disease and somnolence, mainly caused by activating the serotonin 5‐HT2B receptor (5‐HT2BR) and dopamine D3 receptor (D3R), respectively, currently challenge their clinical
Takayuki Suzuki, Fumiki Oana, Masaki Oota, Yuma Handa, Osamu Kaminuma   +4 more
wiley   +1 more source

Cardiovascular Health in Women—Across the Lifespan

Clinical Endocrinology, EarlyView.
ABSTRACT Cardiovascular disease (CVD) remains the leading cause of mortality and morbidity among women worldwide. However, CVD continues to be perceived as a predominantly male issue. CVD in women therefore remains understudied, underrecognized and undertreated.
Jaya Chandrasekhar, Jessica Yao, Simone Gong, Madhuka Wijayarathne, Monique Watts, Swati Mukherjee   +5 more
wiley   +1 more source

Time Course of Ventricular Remodeling after Atrial Septal Defect Closure in Adult Patients

Journal of Chest Surgery, 2021
Background: Atrial septal defect (ASD) is the most common congenital heart disease. However, the details of cardiac chamber remodeling after surgery are not well known, although this is an important issue that should be analyzed to understand long-term
Yo Han Bae, Woo Sung Jang, Jin Young Kim, Yun Seok Kim   +3 more
doaj   +1 more source

Left Ventricular Pacing In Patients With Congestive Heart Failure [PDF]

, 2006
Cardiac resynchronisation therapy (CRT) using biventricular (BIV) pacing has proved its effectiveness to correct myocardial asynchrony and improve clinical status of patients with severe congestive heart failure (CHF) and widened QRS. Despite a different
Etienne, Yves, Jean-Jacques, Blanc, Marjaneh, Fatemi   +2 more
core   +2 more sources