Results 151 to 160 of about 48,927 (270)

Fostamatinib and the risk of acute aortic dissection in immune thrombocytopenia

open access: yesBritish Journal of Clinical Pharmacology, Volume 91, Issue 12, Page 3537-3541, December 2025.
Immune thrombocytopenia (ITP) is a rare autoimmune disorder characterized by platelet destruction. While most patients respond to first‐ or second‐line therapies, a small subset is multirefractory. Fostamatinib, an oral spleen tyrosine kinase (SYK) inhibitor, is a therapeutic option in these cases.
Paul Dalmas   +7 more
wiley   +1 more source

Pulmonary arterial hypertension outcomes upon endothelin-1 receptor antagonist switch to macitentan [PDF]

open access: yes, 2019
Objectives: To assess whether switching patients with suboptimally controlled pulmonary arterial hypertension from bosentan or ambrisentan to macitentan would improve six-minute walk test (6MWT) distance and World Health Organization functional class ...
Gabbay, Eli   +3 more
core   +1 more source

Anterolateral Papillary Muscle Rupture After Acute Myocardial Infarction Leading to Severe Mitral Regurgitation: A Case Report

open access: yesClinical Case Reports, Volume 13, Issue 12, December 2025.
Mitral anterolateral papillary muscle rupture with partial valve body prolapse and severe mitral regurgitation after acute myocardial infarction (ultrasound schematic). ABSTRACT Due to dual blood supply, ischemic mitral anterolateral papillary muscle rupture is less common than that of posteromedial papillary muscle and is rare in acute myocardial ...
Zeyan Liu   +4 more
wiley   +1 more source

Techniques for Identification of Left Ventricular Asynchrony for Cardiac Resynchronization Therapy in Heart Failure [PDF]

open access: yes, 2005
The most recent treatment option of medically refractory heart failure includes cardiac resynchronization therapy (CRT) by biventricular pacing in selected patients in NYHA functional class III or IV heart failure. The widely used marker to indicate left
Peter, Schuster, Svein, Faerestrand
core  

Medical education in the age of artificial intelligence

open access: yesHong Kong Journal of Emergency Medicine, Volume 32, Issue 6, December 2025.
Abstract Background Artificial intelligence (AI) marks an inflection point in medical education systems built on scarcity of resources. These designs privilege standardisation and recall‐heavy examinations over reasoning and adaptive expertise, defined as the capacity to apply knowledge flexibly in uncertain clinical contexts, producing learners who ...
Minyang Chow   +2 more
wiley   +1 more source

Retrospective study of the association between neutering status and changes secondary to degenerative mitral valve disease [PDF]

open access: yes, 2019
Dissertação de Mestrado Integrado em Medicina VeterináriaMyxomatous mitral valve disease is the most common cardiovascular disease reported in dogs. Although many patients may remain asymptomatic, some of them progress to left-sided congestive heart ...
Silva, Ana Margarida Ribeiro da
core  

Additional file 20 of Effect of inferior caval valve implantation on circulating immune cells and inflammatory mediators in severe tricuspid regurgitation

open access: yes
Supplementary Material ...
Mattig, Isabel   +9 more
openaire   +1 more source

A Case of Right‐Sided Heart Failure and Severe Pulmonary Hypertension Secondary to Partial Anomalous Pulmonary Venous Connection

open access: yesRespirology Case Reports, Volume 13, Issue 12, December 2025.
We present a case of isolated partial anomalous pulmonary venous connection (PAPVC) in a 48‐year‐old woman with severe pulmonary hypertension and right‐sided heart failure. CT pulmonary angiography revealed anomalous drainage of the right upper pulmonary vein into the superior vena cava, with no associated atrial septal defect.
Ahmed Tareq Alabsi   +5 more
wiley   +1 more source

Antimicrobial prescribing guidelines for horses in Australia

open access: yesAustralian Veterinary Journal, Volume 103, Issue 12, Page 781-889, December 2025.
The growing problem of antimicrobial resistance also affects equine veterinarians with increasing frequency. Antimicrobial stewardship and responsible prescribing are essential for a future in which effective antimicrobials are available, as it is unlikely that new antimicrobials will become available for use in horses.
L Hardefeldt   +18 more
wiley   +1 more source

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