Results 151 to 160 of about 47,850 (273)

Sickle Cell Diastolic Cardiomyopathy and Mortality Risk: A Novel Echocardiographic Framework for Prognostic Stratification

open access: yesAmerican Journal of Hematology, Volume 100, Issue 11, Page 1940-1951, November 2025.
ABSTRACT Cardiovascular complications are the leading cause of mortality in sickle cell anemia (SCA) patients. While extensive data have identified diastolic dysfunction (DD) to increase morbidity and mortality, the unique hemodynamic conditions inherent to SCA challenge the current recommendations to assess diastolic function. Thus, there is an urgent
Théo Simon   +20 more
wiley   +1 more source

Techniques for Identification of Left Ventricular Asynchrony for Cardiac Resynchronization Therapy in Heart Failure [PDF]

open access: yes, 2005
The most recent treatment option of medically refractory heart failure includes cardiac resynchronization therapy (CRT) by biventricular pacing in selected patients in NYHA functional class III or IV heart failure. The widely used marker to indicate left
Peter, Schuster, Svein, Faerestrand
core  

Ventricular Morphology and Outcomes in Fontan Circulation without Hypoplastic Left Heart Syndrome: A Single-Center's Experience

open access: yesReviews in Cardiovascular Medicine
Background: The impact of dominant ventricular morphology on Fontan patient outcomes remain controversial. This study evaluates long-term results of right ventricle (RV) dominance versus left ventricle (LV) dominance in Fontan circulation without ...
Han Wang   +11 more
doaj   +1 more source

Additional file 20 of Effect of inferior caval valve implantation on circulating immune cells and inflammatory mediators in severe tricuspid regurgitation

open access: yes
Supplementary Material ...
Mattig, Isabel   +9 more
openaire   +1 more source

Right ventricular global work efficiency: A reliable non‐invasive estimate of right ventricular contractility

open access: yesESC Heart Failure, Volume 12, Issue 5, Page 3719-3730, October 2025.
The figure illustrates the study design and key findings related to right ventricular myocardial work (RVMW) in heart failure with reduced ejection fraction (HFrEF) patients with and without pulmonary hypertension (PH). Patients were stratified into two groups: those with PH (n = 53) and those without PH (n = 49), as determined by right heart ...
Paolo Manca   +12 more
wiley   +1 more source

Pattern of Cardiovascular Diseases Among Elderly Patients Admitted in Medical Wards at Muhimbili National Hospital Dar es salaam Tanzania [PDF]

open access: yes, 2011
Cardiovascular disease is the most frequent cause of death in persons over the age 50 years and most importantly it is responsible for considerable morbidity and large burden of disability in the community. Cardiovascular diseases are an increasing cause
Kisenge, Peter Richard
core  

Association of Estimated Plasma Volume Status With Invasive Hemodynamics and Adverse Clinical Outcomes in Patients With Pulmonary Hypertension and Chronic Kidney Disease

open access: yesPulmonary Circulation, Volume 15, Issue 4, October 2025.
ABSTRACT Identifying noninvasive measures to assess intravascular volume status and risk stratify patients with pulmonary hypertension (PH) and chronic kidney disease (CKD) is needed. We assessed the predictive value of estimated plasma volume status (ePVS) using the Strauss‐derived Duarte formula in PH–CKD patients.
Andrew Geller   +12 more
wiley   +1 more source

An Unusual Initial Manifestation of Pulmonary Embolism: Aseptic Cavitary Infarction With Pulmonary Hypertension—Case Report and Literature Review

open access: yesRespirology Case Reports, Volume 13, Issue 10, October 2025.
We report a rare case of CTEPH presenting with an aseptic cavitary pulmonary infarction, an unusual manifestation typically mimicking infection or malignancy. This case underscores the need for genetic screening in unexplained CTEPH, as thrombophilia workup in our case revealed a heterozygous Factor V Leiden mutation (an uncommon congenital risk factor
Vinay Venugopal   +5 more
wiley   +1 more source

Diastolic And Systolic Right Ventricular Dysfunction Precedes Left Ventricular Dysfunction In Patients Paced From Right Ventricular Apex [PDF]

open access: yes, 2006
Background: Cardiac dysfunction after right ventricular (RV) apical pacing is well known but its extent, time frame of appearance and individual effect on left ventricular (LV), RV systolic and diastolic parameters has not evaluated in a systematic ...
Bansal, Sandeep   +7 more
core  

JAK–STAT inhibitory effect of IN‐115314, a novel small molecule inhibitor, and pharmacokinetic/pharmacodynamic study in canine

open access: yesBritish Journal of Pharmacology, Volume 182, Issue 20, Page 5071-5082, October 2025.
Abstract Background and Purpose The JAK–STAT signalling pathway has been extensively spotlighted as a therapeutic target for various diseases. This study assessed the inhibitory effects of a novel small molecule, IN‐115314, on JAK–STAT pathway. Experimental Approach The IC50 values of IN‐115314 for JAK1–pSTAT3 and JAK2–pSTAT5 were determined in canine ...
Jae‐Hun Ahn   +16 more
wiley   +1 more source

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