Results 31 to 40 of about 2,335,384 (342)

Chinese expert consensus on perioperative integrated rehabilitation for radical prostatectomy (2024 edition) [PDF]

Zhongguo aizheng zazhi
Prostate cancer is one of the most common malignancies in men, and radical prostatectomy (RP) is the primary treatment method for localized and locally advanced prostate cancer.
Committee of Integrated Rehabilitation for Urogenital Tumors, Chinese Anti-Cancer Association
doaj   +1 more source

Computational neurorehabilitation: modeling plasticity and learning to predict recovery [PDF]

, 2016
Despite progress in using computational approaches to inform medicine and neuroscience in the last 30 years, there have been few attempts to model the mechanisms underlying sensorimotor rehabilitation.
Burdet, E, Casadio, M, Krakauer, JW, Kwakkel, G, Lang, CE, Reinkensmeyer, DJ, Schweighofer, N, Swinnen, SP, Ward, NS   +8 more
core   +5 more sources

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Sensorimotor Rhythm-Brain Computer Interface With Audio-Cue, Motor Observation and Multisensory Feedback for Upper-Limb Stroke Rehabilitation: A Controlled Study [PDF]

, 2022
Xin Li, Lu Wang, Si Miao, Zan Yue, Zhi‐Ming Tang, Liujie Su, Yadan Zheng, Xiangzhen Wu, Shan Wang, Jing Wang, Zulin Dou   +10 more
openalex   +1 more source

Development of a first-contact protocol to guide assessment of adult patients in rehabilitation services networks [PDF]

, 2016
OBJECTIVE: This paper describes the development of the Protocol for Identification of Problems for Rehabilitation (PLPR), a tool to standardize collection of functional information based on the International Classification of Functioning, Disability and ...
Coster, Wendy J., César, Cibele C., Ferreira, Fabiane R., Furtado, Sheyla R.C., Mancini, Marisa C., Sampaio, Rosana F., Souza, Mariana A.P.   +6 more
core   +4 more sources

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Organizational basis of cardiorehabilitation [PDF]

КардиоСоматика, 2018
Evaluation of long-term experience cardiac rehabilitation in a rehabilitation center "Chyornaya rechka" allowed to formulate general technology rehabilitation of cardiac patients in different categories.
O. F Misyura, V. N Shestakov, I. A Zobenko, A. V Karpukhin, P. V Aleksandrov, A. A Goryunova   +5 more
doaj   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Prediction of functional outcome after spinal cord injury: a task for the rehabilitation team and the patient [PDF]

, 2000
Study design: Descriptive analysis of data gathered in an information system.Objectives: To explore the predictions of professionals and patients regarding functional outcome after spinal cord injury related to the final results after inpatient ...
Eisma, W.H., Groothoff, J.W., Mulder, G.A., Schönherr, M.C.   +3 more
core   +2 more sources