Results 111 to 120 of about 113,384 (303)

Safety and Tolerability of Givinostat: Evidence From Real‐World and Clinical Practice

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The aim of our study was to establish the prevalence of adverse events in a real‐world setting in boys living with Duchenne muscular dystrophy (DMD) treated with givinostat as part of an Expanded Access Program (EAP) in Italy. Methods The cohort included 90 ambulant boys, with age when treatment started between 6 and 23 years (mean ...
Marika Pane   +19 more
wiley   +1 more source

Comprehensive Assessment of Arterial, Tissue, and Venous Collaterals for Evaluating the Infarct Growth Rate: The Multimodal Collateral Score

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Collaterals are crucial factors that influence the infarct growth rate (IGR). We aimed to determine whether a comprehensive multimodal collateral score (MCS), incorporating collateral assessment at the arterial, tissue, and venous levels, is associated with functional independence and provides incremental prognostic value over ...
Giorgio Busto   +12 more
wiley   +1 more source

A Pilot Implementation of an Intervention to Promote Sexual Health in Adolescents and Young Adults in Rehabilitation

open access: yes, 2013
The majority of children treated in pediatric rehabilitation reach adulthood and develop into individuals with needs concerning sexuality and intimate relationships.
Kruijver, E   +3 more
core   +1 more source

Novel prognostic signature unveils PSEN1 contributes to depression-induced lung adenocarcinoma progression

open access: yesFrontiers in Immunology
PurposeDepression is acknowledged to correlate with the occurrence and progression of multiple cancers. However, no study has yet systematically complied depression-related genes to construct a prognostic signature for lung adenocarcinoma (LUAD ...
Qiaoqi Zheng   +18 more
doaj   +1 more source

Remarkable Recovery After Delayed High‐Dose Methylprednisolone in a Rare Case of Penetrating Spinal Cord Injury

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Traumatic spinal cord injury (TSCI) caused by sharp‐force penetration is exceptionally rare, and the use of high‐dose methylprednisolone (MP) remains highly controversial, especially beyond the conventional 8‐h treatment window. This case report describes a 30‐year‐old male with acute incomplete TSCI following a knife stab wound to the right ...
Honghong Wang   +5 more
wiley   +1 more source

White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian   +8 more
wiley   +1 more source

“Physical rehabilitation without vocational rehabilitation is unfinished business”: The IRO’s Rehabilitation Programme for Displaced Persons with Disabilities, 1948‑1952

open access: yesDiasporas: Circulations, Migrations, Histoire
By examining the IRO’s rehabilitation program for DPs with disabilities, this article addresses the question of how rehabilitation was organised and understood by international institutions after the Second World War.
Johannes Glack
doaj   +1 more source

Thalamo‐Lesional Connectivity Signatures of Bilateral Tonic–Clonic Seizures in Focal Cortical Dysplasia‐Related Epilepsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Focal cortical dysplasia (FCD) is the most common etiology of drug‐resistant epilepsy in children. Focal to bilateral tonic–clonic seizures (FBTCS) mark a high risk of drug‐resistant epilepsy and involve thalamocortical circuitry in their generation and propagation.
Hua Xie   +8 more
wiley   +1 more source

Structural Determinants of Boredom Among the Clients of Psychosocial and Vocational Rehabilitation Centers

open access: yes, 2010
In psychosocial rehabilitation programs, clients are encouraged to counter boredom by occupying their time in more structured, meaningful, and enjoyable ways.
Verhaeghe, Mieke   +3 more
core   +1 more source

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