Results 51 to 60 of about 103,986 (215)

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

Psychological features of abstinent heroin users before and after rehabilitation in Saint Petersburg, Russia

BMC Research Notes, 2018
Objective The objective of the study was to describe psychological features of abstinent heroin users undergoing rehabilitation in Saint Petersburg, Russia.
Timofey Galankin, Dmitry Lioznov, Svetlana Nikolaenko, Louise-Anne McNutt, Emily Leckman-Westin, Perry F. Smith   +5 more
doaj   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

A new frontier of pediatric oncology rehabilitation: Establishment of a dedicated working-group within the Italian Association of Pediatric Hematology and Oncology

Journal of Pediatric Rehabilitation Medicine, 2019
PURPOSE: In Italy, most children and adolescents affected by oncological diseases are treated in one of the centers within the Italian Association of Pediatric Hematology and Oncology (AIEOP).
Francesca Rossi, Monica Coppo, Giulia Zucchetti, Federica Ricci, Franca Fagioli   +4 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source

Prevalence of Intestinal Parasitic Infections in Rehabilitation Centers in Golestan Province, Iran

Medical Laboratory Journal, 2014
Background and Objective: Given the importance of having knowledge about intestinal parasitic infections in rehabilitation centers, we aimed to investigate the prevalence of intestinal parasitic infections in the disabled.
M Soosaraie, AS Pagheh, SH Gholami
doaj  

كفــــاءة الــبرامـــج المهنيـــة المقــــدمـــة لـذوى الإعاقـة الفكرية البسيطة في مراكز التأهيل المهني Efficiency of vocational programs provided to people with mild intellectual disabilities in vocational rehabilitation centers [PDF]

مجلة التربیة الخاصة والتأهیل
هدفت الدراسة الى التعرف على مستوى كفاءة البرامج المهنية المقدمة لذوى الإعاقة الفكرية البسيطة في مراكز التأهيل المهني، وتكونت عينة الدراسة من المشرفين على ذوي الاعاقة الفكرية في مراكز التأهيل المهني والبالغ عددهم (٦٧) من الذكور والاناث، كما اعتمدت الدراسة
رؤى الحربي, أميرة مسعود   +1 more
doaj   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source