Results 11 to 20 of about 140,766 (264)

Public spending on orphan medicines: a review of the literature

Journal of Pharmaceutical Policy and Practice, 2020
Background and objective Little is known about how much public payers spend on orphan medicines. This study aimed at identifying information on orphan medicine expenditure incurred by public payers that was published in literature globally and at ...
Margit Gombocz, Sabine Vogler
doaj   +1 more source

Effectiveness of ribociclib in metastatic breast cancer in one hospital in Bulgaria—results from real-world clinical practice [PDF]

Pharmacia
Real-world evidence (RWE) complements randomized clinical trial data by demonstrating treatment effectiveness in routine practice and unselected populations.
Mariyana Eneva, Petya Borisova, Boryana Ivanova, Mila Petrova, Alexandra Savova, Manoela Manova   +5 more
doaj   +3 more sources

Treatment pattern of chronic lymphocytic leukemia/small lymphocytic lymphoma in Korea: a multicenter retrospective study (KCSG LY20-06) [PDF]

The Korean Journal of Internal Medicine, 2023
Background/Aims Little attention is paid to chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) in Korea due to the rarity of the disease.
Jung Sun Kim, Tae Min Kim, Myoung Joo Kang, Sung Ae Koh, Hyunkyung Park, Seung-Hyun Nam, Jae Joon Han, Gyeong-Won Lee, Young Jin Yuh, Hee Jeong Lee, Jung Hye Choi   +10 more
doaj   +1 more source

Real-world effectiveness of dabrafenib and trametinib in patients with BRAF-positive melanoma treated in routine Bulgarian clinical practice [PDF]

Pharmacia
Malignant melanoma is among the leading forms of cancer on a global scale, accounting for 1 in 5 skin cancers. Over the past decades, the treatment of melanoma has significantly improved following the development of therapies such as MAPK molecular ...
Alexandra Savova, Boryana Ivanova, Gergana Shalamanova, Iva Gavrilova, Jeliazko Arabadjiev, Radoslav Mangaldzhiev, Assen Dudov, Daniel Penchev, Martina Nacheva, Lyubomir Bakalivanov, Boryana Zidarova, Dimitrina Apostolova, Mariya Vasileva, Silvia Terezova, Manoela Manova   +14 more
doaj   +3 more sources

Impact of changes in the methodology of external price referencing on medicine prices: discrete-event simulation

Cost Effectiveness and Resource Allocation, 2020
Background Several governments apply the policy of external price referencing (EPR), which considers the prices of a medicine in one or more other countries for the purpose of setting the price in the own country.
Sabine Vogler, Peter Schneider, Lena Lepuschütz   +2 more
doaj   +1 more source

Adequate effectiveness of ribociclib plus letrozole or fulvestrant in patients with advanced or metastatic hormone receptor-positive, human epidermal growth factor receptor 2-negative breast cancer treated in routine Bulgarian clinical practice

Biotechnology & Biotechnological Equipment, 2023
Randomized controlled trials (RCTs) are typically conducted in highly selected patient populations to ideally demonstrate unconfounded clinical efficacy of a drug.
Manoela Manova, Jeliazko Arabadjiev, Radoslav Mangaldzhiev, Assen Dudov, Daniel Penchev, Margit Hemetsberger, Arkadi Sharkov, Boryana Zidarova, Dimitrina Apostolova, Maria Vasileva, Silvia Terezova, Mila Vlaskovska, Alexandra Savova   +12 more
doaj   +1 more source

Access to precision medicine in Thailand: a comparative study [PDF]

Journal of Health Research, 2022
Purpose – This study explored health insurance coverage of genetic testing and potential factors associated with precision medicine (PM) reimbursement in Thailand. Design/methodology/approach – The study employed a targeted review method.
Nisita Jirawutkornkul, Chanthawat Patikorn, Puree Anantachoti   +2 more
doaj   +1 more source

Towards a more transparent HTA process in Poland: new Polish HTA methodological guidelines

Journal of Market Access & Health Policy, 2017
Introduction: Health technology assessment (HTA) in Poland supports reimbursement decisions via the Polish HTA Agency (AOTMiT), whose guidelines were updated in 2016.
Krzysztof Lach, Michal Dziwisz, Cécile Rémuzat, Mondher Toumi   +3 more
doaj   +1 more source

Assessing, Pricing and Funding Point-of-Care Diagnostic Tests for Community-Acquired Acute Respiratory Tract Infections–Overview of Policies Applied in 17 European Countries

Antibiotics, 2022
Point-of-care diagnostic tests for community-acquired acute respiratory tract infections (CA-ARTI) can support doctors by improving antibiotic prescribing.
Sabine Vogler, Friederike Windisch
doaj   +1 more source

Cost-effectiveness of the use of the continuous subcutaneous insulin infusion pump versus daily multiple injections in type 1 diabetes adult patients at the Mexican Institute of Social Security

Cost Effectiveness and Resource Allocation, 2019
Background To estimate the incremental cost-effectiveness ratio (ICER) of the use of continuous subcutaneous insulin infusion (CSII) therapy versus multiple daily injections (MDI) therapy in adult patients with type 1 diabetes (T1D) at the Mexican ...
Svetlana V. Doubova, Stephane Roze, Aldo Ferreira-Hermosillo, Ricardo Pérez-Cuevas, Ricardo Gasca-Pineda, Casper Barsoe, Jonathan Baran, Brian Ichihara, Erick Gryzbowski, Kyla Jones, Juan E. Valencia   +10 more
doaj   +1 more source