Results 101 to 110 of about 37,818 (285)

Efficacy, safety and cost‐effectiveness of CAR‐T therapy

British Journal of Clinical Pharmacology, EarlyView.
CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher, Amina Džidić‐Krivić, Emma Pinjic, Nejra Selak, Kanita Omerbasic, Alexandar Chupin, Andrej Belancic, Almir Fajkic   +7 more
wiley   +1 more source

Mapping heterogeneity in the management of malignant pleural effusions with indwelling pleural catheters in Denmark - a national survey

European Clinical Respiratory Journal
Background Malignant pleural effusion (MPE) affects up to 20% of cancer patients, causing dyspnea and frequent hospitalizations. Treatment includes thoracentesis, pleurodesis, and indwelling pleural catheters (IPC).
Aras K. M. Ali, Katrine Fjaellegaard, Christian B. Laursen, Søren Helbo Skaarup, Karin Armbruster, Uffe Bødtger   +5 more
doaj   +1 more source

Do drugs approved via expedited approval pathways have therapeutic advantages? A systematic review and meta‐analysis

British Journal of Clinical Pharmacology, EarlyView.
Regulators use expedited approval pathways to speed market approval and patient access to promising new drugs. However, there is uncertainty about whether these pathways are successful in approving drugs with significant therapeutic advantages. This systematic review aims to examine the safety, effectiveness and cost‐effectiveness of drugs approved via
Ashleigh Hooimeyer, Eliza J. McEwin, Zhicheng Wang, Joel Lexchin, Barbara Mintzes   +4 more
wiley   +1 more source

Optimal reimbursement schemes in contests

Many contests, such as innovation races or litigation, often involve reimbursement of expenses. This study examines optimal reimbursement schemes in two-player Tullock contests, analyzing four reimbursement structures: external and internal mechanisms ...
Nitsan, Shemu®el, Darioshi, Roy, Cohen, Chen, Chowdhury, Subhasish M.   +3 more
core  

The impact of diagnosis subject to reimbursement on life expectancy, the ability to work, and the quality of life: The experts’ assessment

SHS Web of Conferences, 2014
The ex-post retrospective analysis of the health care reform in Latvia has been performed by several authors; therefore in writing this paper, the author also considered it essential to try and predict its future prospects, specifically, to carry out an ...
Araja D.
doaj   +1 more source

Digital diagnostics, biomarkers and therapeutics in an evolving healthcare system: From promise to practice

British Journal of Clinical Pharmacology, EarlyView.
Abstract Health care is shifting towards a digital‐guided system, integrating digital diagnostics, biomarkers and therapeutics in many care pathways. However, despite rapid technological advancement and preliminary adoption accelerated by the COVID‐19 pandemic, a significant implementation gap persists. This narrative review explores the causes of this
Mees H. P. Stoop, Gertjan J. A. Driessen, Adam F. Cohen, Matthijs D. Kruizinga   +3 more
wiley   +1 more source

Practice, knowledge and attitude of physicians and pharmacists towards the spontaneous reporting system of adverse drug reactions in Switzerland

British Journal of Clinical Pharmacology, EarlyView.
Introduction Introduction Reporting adverse drug reactions (ADRs) is essential for detecting drug risks. Despite legal obligations in Switzerland, underreporting remains an issue. This study assessed practice, knowledge and attitudes towards the spontaneous ADR reporting system among physicians and pharmacists.
Fiona A. Strobel, Thomas Stammschulte, Patrick E. Beeler   +2 more
wiley   +1 more source

Precision medicine in paediatrics: Progress and priorities

British Journal of Clinical Pharmacology, EarlyView.
Precision medicine is revolutionizing personalized healthcare, advancing both diagnostics and therapeutics at an unprecedented pace. Reviewing the paediatric applications of pharmacometrics, pharmacogenomics and advanced therapy medicinal products highlights not only the relevance of these exciting innovations to frontline care but also the significant
Nicola Husain, Claire Booth, Joseph F. Standing, Charlotte I. S. Barker   +3 more
wiley   +1 more source

Why do we need quality measures in emergency medicine?

Journal of the American College of Emergency Physicians Open
Quality measures increasingly influence the delivery and reimbursement of care provided in emergency departments. While emergency physicians are accustomed to using quality measures to improve care delivery, payors, including the Centers for Medicare and
Shamie Das, Gregg Miller, Christopher Libby, Cameron J. Gettel, Elaine Rabin, Michelle Lin   +5 more
doaj   +1 more source

Payment models and reimbursement barriers for remote patient monitoring across healthcare settings: a scoping review protocol

Purpose Remote patient monitoring (RPM) promises better chronic-disease management by allowing clinicians to track patients’ physiological data in real time outside traditional care settings.
Kees Ahaus, Kay Duit, Maureen Rutten-van Mölken, Petra Porte   +3 more
core   +1 more source