Results 91 to 100 of about 99,343 (297)

Clinical effectiveness of procalcitonin‐ or C‐reactive protein‐guided antibiotic discontinuation protocols for adult patients who are critically ill with sepsis: a rapid systematic review and meta‐analysis

open access: yesAnaesthesia, EarlyView.
Summary Introduction Antibiotics are a first‐line treatment for sepsis, with guidelines recommending a 7‐ to 10‐day course. Prolonged antibiotic use carries significant risks, prompting growing interest in using inflammatory biomarkers, such as procalcitonin or C‐reactive protein, to guide clinical decision‐making on the duration of antibiotic therapy ...
Sonya Rafiq   +6 more
wiley   +1 more source

A Bayesian Framework for Parameter Estimation in Dynamical Models with Applications to Forecasting [PDF]

open access: yes, 2009
Mathematical models in Biology are powerful tools for the study and exploration of complex dynamics. Nevertheless, bringing theoretical results to an agreement with experimental observations involves acknowledging a great deal of uncertainty intrinsic to
Claudia T. Codeç, Flá
core   +1 more source

Elimination of Congenital Syphilis in Ukraine: Analysis and the Emerging Issues [PDF]

open access: yes, 2017
The objective of this study is to analyze the indicators of the process of elimination of mother-to-child transmission of syphilis in Ukraine thus helping to prepare for elimination of this process according to the WHO targets and criteria ...
Derevyanko, L. (Lyudmyla)
core   +2 more sources

Driveline Infections Among Patients Supported With Left Ventricular Assist Devices: A Single Center Sixteen‐Year Longitudinal Profile

open access: yesArtificial Organs, EarlyView.
Our study of 1026 LVAD implants revealed HeartWare had lower driveline infection rates than other LVAD types. In addition, severe diabetes was associated with higher risk, while older age and coronary artery disease were linked to a lower risk of driveline infections.
Anh Nguyen   +6 more
wiley   +1 more source

Genetic variation among lambs in peripheral IgE activity against the larval stages of Teladorsagia circumcincta [PDF]

open access: yes, 2010
IgA and IgE activity against Teladorsagia circumcincta was investigated in a flock of Texel lambs following natural, mixed nematode infection among lambs.
Bishop, S.C.   +6 more
core   +1 more source

The Paediatric BCG Vaccine Century: From Historical Success to Future Innovations

open access: yesActa Paediatrica, EarlyView.
ABSTRACT Aim The tuberculosis (TB) vaccine, Bacille‐Calmette‐Guérin (BCG), protects infants against severe forms of primary TB. Yet, it does not protect against pulmonary reactivation TB in adults. Methods A literature review was conducted between 1st January and 28th February 2025 using PubMed, Google Scholar and reports of the World Health ...
Stefan H. E. Kaufmann
wiley   +1 more source

Impact of a treatment as prevention strategy on hepatitis C virus transmission and on morbidity in people who inject drugs [PDF]

open access: yes, 2015
Background: Highly effective direct-acting antiviral (DAA) regimens (90% efficacy) are becoming available for hepatitis C virus (HCV) treatment. This therapeutic revolution leads us to consider possibility of eradicating the virus.
Cousien, Anthony   +5 more
core   +3 more sources

Estimation of the worldwide seroprevalence of cytomegalovirus : a systematic review and meta-analysis [PDF]

open access: yes, 2019
Cytomegalovirus (CMV) infection does not usually produce symptoms when it causes primary infection, reinfection, or reactivation because these three types of infection are all controlled by the normal immune system.
Anderholm   +31 more
core   +2 more sources

Meta‐Analysis: High anti‐HBs Titers are Associated with Significantly Reduced Risk of Hepatitis B Virus Reactivation During Rituximab Treatment

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
This meta‐analysis demonstrates a significantly lower risk for HBV reactivation on rituximab if anti‐HBs is > 100 iU/L (3.5%, CI: 1.8%–6.9%) vs. anti‐HBs between 10 and 100 iU/L (13.8%, CI: 8.8%–20.8%) and anti‐HBs negative (27.3%, CI: 20.0%–36.0%). Thus, if anti‐HBs titer is > 10 iU/L, monitoring could be considered.
Shiva Poola   +4 more
wiley   +1 more source

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