Results 101 to 110 of about 99,343 (297)

Antibodies to glycans dominate the host response to schistosome larvae and eggs: Is their role protective or subversive? [PDF]

, 2001
Multiple exposures of chimpanzees to the radiation-attenuated schistosome vaccine provoked a strong parasite-specific cellular and humoral immune response. Specific IgM and IgG were directed mainly against glycans on antigens released by cercariae; these
Coulson, P.S., Cummings, R.D., Eberl, M., Langermans, J.A.M., Nyame, A.K., Thomas, A.W., Vervenne, R.A., Wilson, R.A.   +7 more
core   +1 more source

The presence of a sinus tract is associated with reinfection after two-stage revision surgery for prosthetic hip joint infection: a case-control study

BMC Musculoskeletal Disorders
Background Reinfection rates after two-stage revision (TSR) for prosthetic joint infection (PJI) range from 7.9 to 14%. Many factors, including sinus tracts, are associated with reinfection after this procedure.
Hongjun Xu, Songlin Li, Sen Liu, Shanni Li, Zhaojing Yin, Yiyang Du, Xisheng Weng, Wenwei Qian   +7 more
doaj   +1 more source

Epoxy resin‐based sealers modified with clay nanoparticles: Evaluation of their physicochemical and mechanical properties

European Journal of Oral Sciences, EarlyView.
Abstract Epoxy resin‐based sealers are commonly used in endodontic treatment due to their superior physicochemical properties. Therefore, it is important to utilize these materials by enhancing their properties. Nonetheless, several of their properties remain suboptimal, including the relatively prolonged setting time, the moderate yet clinically ...
Fotis Dimopoulos, Konstantinos Kodonas, Alexandros K. Nikolaidis, Elisabeth A. Koulaouzidou, Nikolaos Economides, Christos Gogos   +5 more
wiley   +1 more source

Investigating the molecular mechanisms underlying the anti‐CRISPR function of AcrIIA13b protein

The FEBS Journal, EarlyView.
Anti‐CRISPR protein AcrIIA13b inhibits CRISPR–Cas9 function by preventing target DNA engagement. The Cas9–sgRNA ribonucleoprotein (RNP) normally recognizes the protospacer adjacent motif (PAM) duplex to initiate DNA cleavage. AcrIIA13b binding to the PAM‐interacting WED–PI domain blocks this recognition, leaving the target DNA intact.
So Yeon Lee, Hyun Ho Park
wiley   +1 more source

In vivo assessment of drug efficacy against Plasmodium falciparum malaria: duration of follow-up. [PDF]

, 2004
To determine the optimum duration of follow-up for the assessment of drug efficacy against Plasmodium falciparum malaria, 96 trial arms from randomized controlled trials (RCTs) with follow-up of 28 days or longer that were conducted between 1990 and 2003
Adjuik, M, Barnes, K, Day, N P J, Farrar, J, Guthmann, J P, Hien, T T, Looareesuwan, S, Mayxay, M, Myint, H Y, Nosten, F, Olliaro, P, Price, R, Pukrittayakamee, S, Smithuis, F, Stepniewska, K, Taylor, W R J, White, N J   +16 more
core   +3 more sources

Characterizing risk behaviour and reinfection rates for successful programs to engage core transmitters in HCV elimination (C-RESPECT) [PDF]

, 2021
Brian Conway, Dan Smyth, Réjean Thomas, Alex Wong, Giada Sebastiani, Curtis Cooper, Hemant Shah, Ritesh Kumar, Gretty Deutsch, Ted Watson   +9 more
openalex   +1 more source

Towards inclusive HIV cure development: Identifying important and acceptable HIV cure attributes and strategies among people with HIV in the Netherlands

HIV Medicine, EarlyView.
Abstract Objectives Initial HIV cure interventions may not meet expert‐defined target product profiles (TPPs; desired treatment attributes). Understanding how people with HIV perceive ideal and likely HIV cure attributes is essential. This study examined which optimal TPP attributes people with HIV consider important and which minimum attributes and ...
Maaike A. J. Noorman, John B. F. de Wit, Tamika A. Marcos, Sarah E. Stutterheim, Thijs Albers, Kai J. Jonas, Chantal Den Daas   +6 more
wiley   +1 more source

HCV reinfection incidence and spontaneous clearance rates in HIV-positive men who have sex with men in Western Europe [PDF]

, 2016
BACKGROUND & AIMS: Moderate cure rates of acute hepatitis C virus (HCV) infections with pegylated interferon and ribavirin have been described in the last decade in men who have sex with men (MSM), who are also coinfected with the human immunodeficiency ...
Baumgarten, A, Bhagani, S, Boesecke, C, Bottero, J, Ingiliz, P, Lacombe, K, Mandorfer, M, Martin, TC, Mauss, S, NEAT study group, ., Nelson, M, Rockstroh, JK, Rodger, A, Stellbrink, HJ   +13 more
core  

Transition from endemic behavior to eradication of malaria due to combined drug therapies: an agent-model approach [PDF]

, 2019
We introduce an agent-based model describing a susceptible-infectious-susceptible (SIS) system of humans and mosquitoes to predict malaria epidemiological scenarios in realistic biological conditions.
Lind, Pedro G., Louçã, Jorge, Mendes, António M., Sequeira, João   +3 more
core   +2 more sources

Neutralizing Antibody-Mediated Protection from Prior Delta Variant Infection Against Omicron BA.5 Sub-Lineage Reinfection One Year Later: A Prospective Cohort Study

Vaccines
Background: Previous SARS-CoV-2 infection provides some level of protection against reinfection. However, few studies have evaluated the neutralizing antibody (NAb) response after Delta variant infection and its ability to prevent reinfection with ...
Shihan Zhang, Yin Wang, Guo Xu, Chen Dong, Hua Tian, Chuchu Li, Xiaoxiao Kong, Jiefu Peng, Haodi Huang, Aidibai Simayi, Fengcai Zhu, Jianli Hu, Ke Xu, Changjun Bao, Hui Jin, Liguo Zhu   +15 more
doaj   +1 more source