Results 131 to 140 of about 99,820 (282)

Krisanaklan Reduces Intestinal Anion and Fluid Secretion Through Inhibition of Na+/K+‐ATPase and K+ Channel Activity

Annals of the New York Academy of Sciences, EarlyView.
Krisanaklan reduces CFTR‐dependent intestinal chloride and fluid secretion by inhibiting the Na+,K+‐ATPase and K+ channels in epithelial cells. Consequently, this natural, plant‐derived product may limit secretory diarrhea caused by a diverse array of microbial pathogens. However, by dissipating the transmembrane Na+ gradient, Krisanaklan also inhibits
Tessa A. Groeneweg, Erdene Baigal, Anny Leung, Gert‐Jan Kremers, Marcel J. C. Bijvelds   +4 more
wiley   +1 more source

Novel and emerging antimicrobial strategies in the management of oral infections

Periodontology 2000, EarlyView.
Abstract Background Antibiotics marked a pivotal turning point in human civilization, enhancing social interactions and extending human life expectancy. In addition to their success in treating systemic infectious diseases, they have significantly improved periodontal treatment outcomes as an adjunct therapy.
Ozge Unlu, Nil Yakar, Alpdogan Kantarci
wiley   +1 more source

The impact of illicit drug use on Spontaneous Hepatitis C Clearance: Experience from a large cohort population study [PDF]

, 2011
Background and Aims: Acute hepatitis C infection usually ends in chronic infection, while in a minority of patients it is spontaneously cleared. The current population-based study is performed on a large cohort in Golestan province of Iran to examine the
Esmaili, S., Malekzadeh, R., Merat, S., Mohamadkhani, A., Nikmahzar, A., Pourshams, A., Poustchi, H., Sepanlou, S.G.   +7 more
core  

Artemisinin‐Based Combination Therapies in East Africa: A Systematic Review of Quality, Clinical Efficacy, and Regulatory Progress Towards Sustainable Malaria Control

Tropical Medicine &International Health, EarlyView.
ABSTRACT Background Malaria is a major public health issue in East Africa, leading to widespread illness and fatalities, especially among vulnerable populations such as children under 5 years of age and pregnant women. Artemisinin‐based combination therapies (ACTs) are the primary treatment modality; however, their efficacy is undermined by the ...
Yesuneh Tefera Mekasha, Addisu Afrassa Tegegne, Tapfumanei Mashe, Million Girma, Gemmechu Hasen, Sileshi Belew   +5 more
wiley   +1 more source

A Randomised Trial of Three Face‐Washing Methods for the Removal of Chlamydia trachomatis From the Faces of Children With Severe Active Trachoma

Tropical Medicine &International Health, EarlyView.
ABSTRACT Objectives A three‐arm, open, parallel‐group randomised trial compared three face‐washing methods for cleaning Chlamydia trachomatis from the faces of children with severe active trachoma. The impact of face‐washing on Chlamydia trachomatis on the hands of children and their caregivers and Chlamydia trachomatis duration on faces and hands were
Katie Greenland, Robert Butcher, Edao Sinba Etu, Wake Abebe, Mesfin Bekele, Gebeyehu Dumessa, Yohannes Sitotaw Addisie, Amen Tessema Ariya, Anthony W. Solomon, Alexandra Czerniewska, David Macleod, Anna Last, Oumer Shafi Abdurahman, Matthew J. Burton, Aida Abashawl, Wondu Alemayehu   +15 more
wiley   +1 more source

Prevalence of Intestinal Parasitic Infections and Associated Factors Among Rural Ghanaian School Children: A Cross‐Sectional Study in Tokuroano, Krachi East Municipality

Public Health Challenges, Volume 5, Issue 1, March 2026.
Over 63% of schoolchildren in rural Ghana's Tokuroano area had intestinal parasitic infections, mainly Ascaris, Hookworm, and Giardia. Poor sanitation, unsafe water, and poor hygiene were key risks. Protective factors included home‐cooked meals and health education. Integrated deworming, sanitation, and education programs are urgently needed to address
Christopher Yaw Dumevi, Prince Wise Amekudi, Nana Aba Setorwu Eyeson, Hugette Naa Ayele Aryee, Joyce Junior Asiamah, Ezekiel Kofi Vicar, James‐Paul Kretchy, Simon Sovoe, Saviour Kweku Adjenti, Nicholas T. K. D. Dayie, George Boateng Kyei, Patience B. Tetteh‐Quarcoo, Irene Ayi, Patrick F. Ayeh‐Kumi   +13 more
wiley   +1 more source

Declining Trends in Gastrointestinal Parasitic Infections Among Nepalese School Children: A Systematic Review and Meta‐Analysis (2004–2022)

Public Health Challenges, Volume 5, Issue 1, March 2026.
This meta‐analysis of 25 studies (17,628 children) shows a substantial decline in gastrointestinal parasitic infections in Nepal from 43.4% to 24.2% between 2004 and 2022. Helminths (20.0%) remained more common than protozoa (9.9%), with slightly higher prevalence in urban (29.0%) than rural areas (27.9%). ABSTRACT Background Gastrointestinal parasitic
Jitendra Gautam, Niten Bharati, Shristi Bhandari, Darwin Niroula, Anisha K. C., Pitambar Dhakal, Kishor Pandey, Oskar Nowak, Rajendra Prasad Parajuli   +8 more
wiley   +1 more source

Evolution of hepatitis B virus liver disease after hepatic replacement. Practical and theoretical considerations [PDF]

, 1990
The morphologic evolution of hepatitis B virus (HBV) liver disease in 45 hepatic allograft recipients who were HBV surface-antigen positive (HBs-Ag+) at the time of liver replacement and who survived for more than 60 days was studied by routine ...
Demetris, AJ, Fung, JJ, Iwaki, Y, Ming, W, Starzl, TE, Sysyn, G, Todo, S, Trager, J, Van Thiel, DH   +8 more
core   +1 more source

Multilocus Parasite Gene Polymorphism and/or Parasite-Selected Mutations in Host Genome May Discriminate Between Relapse and Reinfection in the Failure of Miltefosine Treatment in Visceral Leishmaniasis [PDF]

, 2013
Sushmita Das
openalex   +1 more source

Evidence of SARS-CoV-2 Reinfection: Analysis of 35,000 Subjects and Overview of Systematic Reviews

, 2022
V.L. Pecoraro, Tommaso Pirotti, Tommaso Trenti   +2 more
openalex   +1 more source