Disease Progression Mathematical Modeling With a Case Study on Hepatitis B Virus Infection
CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 420-434, March 2025.ABSTRACT Chronic Hepatitis B presents a significant health and socioeconomic burden. The risk of hepatocellular carcinoma remains elevated although treatments are available. Achieving an optimal treatment regimen necessitates a deep comprehension of the dynamic relationship between the virus and its host across disease states.
Clémence Boivin‐Champeaux +6 more
wiley +1 more source
Varying efficacy of artesunate+amodiaquine and artesunate+sulphadoxine-pyrimethamine for the treatment of uncomplicated falciparum malaria in the Democratic Republic of Congo: a report of two in-vivo studies [PDF]
, 2009 BACKGROUND: Very few data on anti-malarial efficacy are available from the Democratic Republic of Congo (DRC). DRC changed its anti-malarial treatment policy to amodiaquine (AQ) and artesunate (AS) in 2005.
A Brockman +32 more
core +2 more sources
Alterations of the oral microbiome in patients reinfected with SARS‐CoV‐2 omicron variants
VIEW, EarlyView.We studied the oral microbiome (the community of microbes in the mouth) in people who were reinfected with the omicron variant of SARS‐CoV‐2 and compared it with healthy individuals and other respiratory illness groups. By sequencing tongue‐coating samples from large cohorts, we identified microbial shifts linked to Omicron reinfection and built a ...
Benchen Rao +17 more
wiley +1 more source
Communications MedicineBackground Although the COVID-19 pandemic has persisted for over 3 years, reinfections with SARS-CoV-2 are not well understood. We aim to characterize reinfection, understand development of Long COVID after reinfection, and compare severity of ...
Emily Hadley +16 more
doaj +1 more source
Many roads to reservoirs? How susceptibility and shedding shape host competence in amphibians
Functional Ecology, EarlyView.Read the free Plain Language Summary for this article on the Journal blog. Abstract Host competence—the ability to acquire, harbour and transmit infections—drives pathogen spread and persistence in multi‐host communities. Evaluating species‐specific competence is critical for predicting transmission, particularly for generalist fungal pathogens like ...
Joseph A. DeMarchi +7 more
wiley +1 more source
Pathogenesis of feline enteric coronavirus infection. [PDF]
, 2008 Fifty-one specific pathogen-free (SPF) cats 10 weeks to 13 years of age were infected with a cat-to-cat fecal-oral passed strain of feline enteric coronavirus (FECV). Clinical signs ranged from unapparent to a mild and self-limiting diarrhea. Twenty-nine
Allen, Claire E +2 more
core
Australian Endodontic Journal, EarlyView.ABSTRACT The sealing performance of endodontic sealers may be influenced by environmental factors such as pH and blood‐derived proteins. This in vitro study evaluated the effects of pH variation and protein contamination on calcium ion (Ca2+) release and push‐out bond strength (BS) of a calcium silicate‐based sealer (Bio‐C Sealer) and an epoxy resin ...
Walter Raucci‐Neto +6 more
wiley +1 more source
Limited asymptomatic carriage of Pneumocystis jiroveci in human immunodeficiency virus-infected patients [PDF]
, 2003 Forty-seven bronchoalveolar lavage fluid samples from 16 human immunodeficiency virus (HIV)-infected patients were used to test the latency model of Pneumocystis infection in the human host.
Ambrose, HE +4 more
core
Different methodological approaches to the assessment of in vivo efficacy of three artemisinin-based combination antimalarial treatments for the treatment of uncomplicated falciparum malaria in African children. [PDF]
, 2008 BACKGROUND: Use of different methods for assessing the efficacy of artemisinin-based combination antimalarial treatments (ACTs) will result in different estimates being reported, with implications for changes in treatment policy.
A Yeka +43 more
core +5 more sources
Comparative Study about the Effectiveness of Certain Vaccines Against SARS-CoV-2 Reinfection among Iraqi Population [PDF]
International Journal of BiomedicineBackground: With the continuation of the COVID-19 pandemic, some COVID-19 patients have a risk of SARS-CoV-2 reinfection. Viral gene sequencing has found that some of these patients were reinfected by a different and others by the same strains.
Karam Al-Akkam +4 more
doaj +1 more source