Results 131 to 140 of about 147,326 (301)

Effective Structural Concrete Repair, Volume 2 of 3, Use of FRP to Prevent Chloride Penetration in Bridge Columns; TR-428, March 2004 [PDF]

, 2004
Structural concrete is one of the most commonly used construction materials in the United States. However, due to changes in design specifications, aging, vehicle impact, etc.

core  

Cis‐ and Trans‐Regulatory Factors Independently Shape Phenotypic Heterogeneity of Retinitis Pigmentosa

Advanced Science, EarlyView.
A zebrafish model carrying an identical human RHO S334X allele reveals two independent genetic layers shaping retinitis pigmentosa (RP) severity: a protective 3‐bp cis‐regulatory insertion that attenuates transgene expression, and a dominant trans‐acting modifier that restores a severe phenotype.
Cong Cui, Kotone Nakagawa, Takumi Tateno, Ayaka Dan, Dexin Meng, Yoshihiro Omori, Soma Tomihara, Suzuri Okamoto, Shigeru Sato, Motokazu Tsujikawa   +9 more
wiley   +1 more source

Dose‐Dependent Reprogramming of Chromatin Accessibility by SOX4 Drives the Transcriptional Response to Iron Overload

Advanced Science, EarlyView.
This study demonstrates that iron overload triggers widespread chromatin compaction and transcriptional repression in human granulosa cells, recapitulating features of endometriosis. The epigenetic reprogramming is orchestrated by a TFEB‐SOX4‐SWI/SNF axis, with SOX4 acting as a central, dosage‐sensitive regulator.
Feifei Li, Yaoqiu Wu, Guangyu Yang, Jingyi Lai, Xiaoyue Sun, Liyan Wang, Xiaoli Li, Jing Zhang, Qingxue Zhang, Hui Chen, Haiyan Lin, Bingxiang Xu, Junfeng Zhang, Hailong Wang, Anming Meng, Chunwei Cao   +15 more
wiley   +1 more source

Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy

Advanced Science, EarlyView.
Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu, Mengtao Sun, Lusheng Li, Jieqiong Wang, Shibiao Wan   +4 more
wiley   +1 more source

Behaviour of GFRP rebars reinforced concrete elements under elevated temperature and fire

, 2003
PhDIn general, it is expected that concrete structures using Glass Fibre Reinforced Plastic (GFRP) rebars as reinforcement could have improved durability compared to normal steel reinforcement because of the corrosion resistance of the rebar. However,
Dezfouli, Abdolkarim Abbasi
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Time-dependent analysis of continuous precast prestressed concrete beams. [PDF]

, 1999
A literature survey on the subject of construction, analysis and design of precast prestressed concrete beams made continuous has been conducted from which various methods of achieving continuity between the precast units have been identified.
Jaafar, Mohd Saleh
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ML Workflows for Screening Degradation‐Relevant Properties of Forever Chemicals

Advanced Science, EarlyView.
The environmental persistence of per‐ and polyfluoroalkyl substances (PFAS) necessitates efficient remediation strategies. This study presents physics‐informed machine learning workflows that accurately predict critical degradation properties, including bond dissociation energies and polarizability.
Pranoy Ray, Andrew R. Castillo, Manoj Kolel‐Veetil, Surya R. Kalidindi   +3 more
wiley   +1 more source

Predictive Modeling and Equation Formulation for 3D-Printed Reinforced Concrete Beams

Advances in Materials Science and Engineering
This study focuses on developing predictive models and design equations for 3D-printed reinforced concrete beams, utilizing machine learning to enhance the accuracy of structural analysis.
Paschal Chimeremeze Chiadighikaobi, Mohammad Hematibahar, Amirali Milani, Makhmud Kharun, Qais Abdulrahman Ali Qais   +4 more
doaj   +1 more source

Ethical Precision in Nanoscale Brain Interfacing

Advanced Science, EarlyView.
As brain interfaces approach the nanoscale, precision no longer only measures—it knows, predicts, and potentially reshapes the mind. This work argues that traditional ethics fails under such conditions and proposes a shift toward continuous, operation‐based governance using the recovery–discovery framework to track, constrain, and responsibly steer ...
Guilherme Wood
wiley   +1 more source

Finite elements for modeling of localized failure in reinforced concrete [PDF]

, 2013
In this work, several beam finite element formulations are proposed for failure analysis of planar reinforced concrete beams and frames under monotonic static loading.
Jukić, Miha
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