Results 61 to 70 of about 7,290 (265)

PolyG Fibrils Coalesce Into Nuclear Ribbons That Engage Proteostasis Machinery in Neuronal Intranuclear Inclusion Disease

Advanced Science, EarlyView.
In NIID, expanded NOTCH2NLC repeats give rise to nuclear polyG inclusions. Tracer‐guided in situ cryo‐electron tomography enables cross‐scale structural analysis from mouse brain to native neuronal nuclei, revealing dense‐core/peripheral‐halo inclusions built from compact polyG ribbons.
Hui Dong, Yongcheng Pan, Zhiyao Tang, Yuxuan Yao, Guicong Zhang, Junpu Wang, Haonan Xiao, Yun Tian, Beisha Tang, Dan Li, Qiang Guo, Ruijun Tian, Qiong Liu, Cong Liu   +13 more
wiley   +1 more source

Automating AI Discovery for Biomedicine Through Knowledge Graphs and Large Language Models Agents

Advanced Intelligent Discovery, EarlyView.
This work proposes a novel framework that automates biomedical discovery by integrating knowledge graphs with multiagent large language models. A biologically aligned graph exploration strategy identifies hidden pathways between biomedical entities, and specialized agents use this pathway to iteratively design AI predictors and wet‐lab validation ...
Naafey Aamer, Muhammad Nabeel Asim, Shan Munir, Andreas Dengel   +3 more
wiley   +1 more source

Cell Segmentation Beyond 2D—A Review of the State‐of‐the‐Art

Advanced Intelligent Discovery, EarlyView.
Cell segmentation underpins many biological image analysis tasks, yet most deep learning methods remain limited to 2D despite the inherently 3D nature of cellular processes. This review surveys segmentation approaches beyond 2D, comparing 2.5D and fully 3D methods, analyzing 31 models and 32 volumetric datasets, and introducing a unified reference ...
Fabian Schmeisser, Haseeb Muhammad, Junaid Younas, Gillian Lovell, Bianca Migliori, Andreas Dengel, Sheraz Ahmed   +6 more
wiley   +1 more source

Flexural capacity of concrete beams reinforced with steel and fibre‐reinforced polymer (FRP) bars

Journal of Civil Engineering and Management, 2004
Although much research on concrete beams reinforced with fibre‐reinforced polymer (FRP) rods has been conducted in recent years, their use still does not receive the attention it deserves from practicising engineers. This is attributed to the fact that
Hau Yan Leung
doaj   +1 more source

Artificial Intelligence and Access to Justice at the ‘Shop Front’: The Potential and Limitations of Meeting Legal Need Through Technology

Australian Journal of Social Issues, EarlyView.
ABSTRACT In Australia, governments fund Community Legal Centres (CLCs) as part of the legal assistance sector (LAS) to meet the ‘legal needs’ of people experiencing disadvantage who cannot afford private legal services. Persistent unmet demand for CLCs is well‐documented. As artificial intelligence (AI) is increasingly used in private legal practice to
Catherine Hastings, Art Cotterell, Farzana Bruce   +2 more
wiley   +1 more source

Innervation of the tubarial glands: A hypothesis‐driven anatomical review

The Anatomical Record, EarlyView.
Abstract The tubarial glands have been described as a macroscopic bilateral glandular complex in the posterolateral nasopharynx near the torus tubarius and the pharyngeal opening of the Eustachian tube. Since their recognition on prostate‐specific membrane antigen‐based imaging, their anatomical classification has remained debated, with converging ...
Mugurel Constantin Rusu, Ivan Varga, Răzvan Costin Tudose   +2 more
wiley   +1 more source

Perilaku Geser pada Keadaan Layan dan Batas Balok Beton Bertulang Berlubang Memanjang

Semesta Teknika, 2016
I cross-section of reinforced concrete reduces weight and concrete needs, but the reduction in strength is not considerably large. In addition, I section reinforced concrete beam is relatively complicated and takes much longer time for manufacturing ...
Wiku A Krasna, Djoko Sulistyo, Bambang Supriyadi   +2 more
doaj  

Flexural Capacity of the Normal Sections of Concrete Beams Strengthened with Corrugated Steel Plates

Buildings
To explore the law of load-carrying performance enhancement of concrete beams reinforced with corrugated steel plates (CSPs), three groups of controlled bending tests were conducted on five beam specimens.
Xianda Feng, Dejun Liu, Xiao Long, Kang Duan, Jianping Zuo, Wei Liu, Haiyang Dong   +6 more
doaj   +1 more source

Eco‐Innovation, Economic Complexity, and Sustainability: A Bibliometric and Systematic Literature Review

Business Strategy and the Environment, EarlyView.
ABSTRACT This study systematizes the literature on eco‐innovation and economic complexity, aiming to understand how the sophistication of productive structures shapes countries' capacity to develop environmentally responsible innovations, and how eco‐innovation may, in turn, influence productive sophistication.
Gregory Matheus Pereira de Moraes, Diogo Ferraz   +1 more
wiley   +1 more source

Selection and Analysis of Beam Column Joints of Multilayer Reinforced Concrete Frame Based on Finite Element

Chemical Engineering Transactions, 2018
At present, there are many tests on the joints of reinforced concrete frame beams and columns, and the corresponding measures have been taken to ensure the strength and ductility of the joints.
Songan Liu, Yafei Liu
doaj   +1 more source