Results 141 to 150 of about 1,717,828 (345)

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

Achieving Balanced Load Distribution with Reinforcement Learning-Based Switch Migration in Distributed SDN Controllers [PDF]

, 2021
Sangho Yeo, Ye Naing, Taeha Kim, Sangyoon Oh   +3 more
openalex   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Mathematical Modeling and Finite Element Analysis of Residual Stress (RS) Field after Multipass Ultrasonic Surface Rolling

Advances in Materials Science and Engineering
In order to achieve the change rule of the induced residual stress (RS) field after multipass ultrasonic surface rolling (USR), a mathematical model of the induced residual stress (RS) field after multipass ultrasonic surface rolling is first established.
Jinggan Shao, Zhanshu He, Genshang Wu, Zhi Zhang, Chao Li   +4 more
doaj   +1 more source

Inaccessibility of reinforcement increases persistence and signaling behavior in the fox squirrel (Sciurus niger).

, 2016
Mikel Delgado, Lucia F. Jacobs
openalex   +1 more source

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

Quantitative Evaluation of Internal Pavement Distresses Based on 3D Ground Penetrating Radar

The Baltic Journal of Road and Bridge Engineering
Asphalt pavement will inevitably produce internal distresses during service, which increases the risk of deterioration of pavement structural performance.
Yong Liu, Zhiwen Zhang, Yang Yuan, Yunsheng Zhu, Kaifeng Wang   +4 more
doaj   +1 more source

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

FEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc, Blaž Stres, Mirica Karlovits, Igor Karlovits, Petra Jerič, Ondrej Panák, Anja Verbič, Blaž Likozar, Uroš Novak   +8 more
wiley   +1 more source

Probability Statistical Model for Measured Ground Motion Based on Generalized Extreme Value Distribution

Shanghai Jiaotong Daxue xuebao
To develop a probability distribution model of peak ground acceleration, 255365 ground motion recordings are collected from 500 stations to create initial statistical samples of peak ground acceleration.
FENG Pengfei, ZHOU Mi, LI Zhixuan, ZHU Guoqiang
doaj   +1 more source