Results 231 to 240 of about 44,679 (297)

Dupilumab as an effective therapy for eosinophilic esophagitis in pediatric patients weighing less than 15 kilograms

open access: yesJPGN Reports, EarlyView.
Abstract Objectives Eosinophilic esophagitis (EoE) is a type 2 cytokine‐mediated chronic inflammatory condition leading to esophageal dysfunction. Dupilumab blocks IL‐4 and IL‐13 signaling, which are key inflammatory mediators in EoE and other allergic disorders.
Sindhura Kasturi   +6 more
wiley   +1 more source

Mapping the Influence of Ansoff's Corporate Strategy

open access: yesStrategic Change, EarlyView.
ABSTRACT This paper conducts a systematic, data‐driven analysis of H. Igor Ansoff's enduring impact on strategic management scholarship. Despite Ansoff's recognition as the “father of strategic management” and the continued relevance of his frameworks—including the Ansoff matrix, weak signals analysis, and strategic thrust—a comprehensive understanding
Ivan Zupic   +3 more
wiley   +1 more source

Long‐Term Dermoscopic Evolution of Reticular Erythematous Mucinosis: Case Report

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Reticular erythematous mucinosis is a rare dermatosis with a challenging diagnosis. To date, its dermoscopic features have not been well characterised in the literature. Only a limited number of case reports have described dermoscopic findings that may be indicative of the disorder, including the presence of dotted and linear vessels, as well ...
Grażyna Kamińska‐Winciorek   +4 more
wiley   +1 more source

Alogliptin Reduces Oxidative Stress in Cardiomyocytes and Ameliorates Diabetic Cardiomyopathy via the AURKB/NLGN2 Signaling

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Diabetic cardiomyopathy (DCM) is a common complication of diabetes mellitus. This study investigated the effects of alogliptin on DCM and its underlying mechanisms. A DCM model was constructed and treated with alogliptin. Downstream targets of alogliptin were screened using bioinformatics analysis.
Li‐Jing Jiao   +7 more
wiley   +1 more source

Correction: The mitochondrial genome sequence of the Bornean orang-utan (Pongo pygmaeus) malaria parasite, Plasmodium pitheci. [PDF]

open access: yesMalar J
Dharmayanthi AB   +16 more
europepmc   +1 more source

Fat Mass and Obesity‐Associated Protein Contributes to Tumorigenesis and Drug Resistance of Diffuse Large B‐Cell Lymphoma by Suppressing N6‐Methyladenosine Methylation of Myc

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Ibrutinib resistance remains a major obstacle in the treatment of diffuse large B‐cell lymphoma (DLBCL). Fat mass and obesity‐associated protein (FTO) has been implicated in drug resistance through its regulation of N6‐methyladenosine (m6A) modifications; however, whether FTO mediates ibrutinib resistance in DLBCL remains unclear.
Ting‐Ting Lu   +5 more
wiley   +1 more source

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