Physiological media and oxygen levels modulate cancer hallmarks in cultured breast cancer cells
MCF7 breast cancer cells were cultured in standard conditions (18% O2 and DMEM) and physiological conditions (5% O2 and Plasmax, a medium modeled after the human plasma metabolome). A combined transcriptomic and proteomic approach was used to identify gene expression signatures at the mRNA and protein levels upstream of functional enrichment analyses ...
Jacob E. Wiebe +5 more
wiley +1 more source
A guide to transcriptional cyclin‐dependent kinases in cancer
Transcriptional cyclin‐dependent‐kinases (tCDKs) facilitate gene expression by promoting RNA polymerase II (RNAPII) progression through discrete phases of the transcription cycle. Aberrant tCDK activity is detectable in different human cancers, thereby contributing to de‐regulated gene expression programs that drive oncogenic phenotypes.
Jennifer R. Devlin +2 more
wiley +1 more source
Home Production and Gender Gap in Structural Change
ABSTRACT The gender gap in non‐agricultural employment in developing countries is concentrated among rural married workers. Within‐family specialization is central: Married women spend more time on home production, work fewer market hours, and are less likely to incur fixed costs of entering non‐agriculture.
Huoqing Cao, Chaoran Chen, Xican Xi
wiley +1 more source
On Spatial Point Processes With Composition‐Valued Marks
Summary Methods for marked spatial point processes with scalar marks have seen extensive development in recent years. While the impressive progress in data collection and storage capacities has yielded an immense increase in spatial point process data with highly challenging non‐scalar marks, methods for their analysis are not equally well developed ...
Matthias Eckardt +2 more
wiley +1 more source
Effect of Remote Vital Signs Monitoring in People Receiving Long-Term Oxygen Therapy: Protocol for a Randomized Controlled Trial. [PDF]
Reis ERMD +5 more
europepmc +1 more source
Genetic Determination of Maternal Behaviour in Pigs
ABSTRACT In sows, maternal behaviour is a commercially important trait which affects sow and piglet welfare and the quality and safety of human‐animal interactions, especially if free farrowing of sows without crates is in place. The aim of this study was to evaluate maternal behaviour and to estimate its quantitative genetic parameters in Swiss ...
Nicole Maffezzini +5 more
wiley +1 more source
The Effect of the Gutta Condensor on Powder-Liquid and Ready-to-Use Hydraulic Sealers. [PDF]
da Siqueira Felske G +6 more
europepmc +1 more source
The worldwide burden of skin diseases: Lessons from the Global Burden of Disease data
Skin diseases are a major public health concern worldwide, causing significant personal, economic and social burdens. The Global Burden of Disease (GBD) initiative provides valuable insights but underestimates the burden of skin diseases, emphasizing the urgent need for improved data collection and global collaboration among stakeholders.
Luigi Naldi +16 more
wiley +1 more source
In vitro and in vivo biocompatibility and bioactivity of bioceramic repair materials. [PDF]
Arantes LC +13 more
europepmc +1 more source
Consensus on energy‐based devices for keloids and hypertrophic scars: A Latin American Delphi study
Latin American Delphi consensus supports a sequential, multimodal approach to keloids and hypertrophic scars: vascular devices for early/inflammatory lesions; intralesional triamcinolone + 5‐fluorouracil and other injectable drugs for active scars; fractional lasers for texture; and pigment‐targeting therapies for dyschromia, prioritizing safety in ...
Gisele Viana de Oliveira +24 more
wiley +1 more source

