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Donor-Derived Cell-Free DNA as a Non-Invasive Biomarker for Graft Rejection in Kidney Transplant Recipients: A Prospective Study among the Indian Population

open access: yesDiagnostics, 2023
Monitoring graft health and detecting graft rejection is crucial for the success of post-transplantation outcomes. In Western countries, the use of donor-derived cell-free DNA (dd-cfDNA) has gained widespread recognition as a diagnostic tool for kidney ...
Naveen Kumar   +13 more
doaj   +1 more source

CSA-Induced PRES after Heart Transplantation—Report of Two Cases and Review

open access: yesThe Thoracic & Cardiovascular Surgeon Reports, 2021
Background Posterior reversible encephalopathy syndrome (PRES) is a rare neurological disease possibly associated with the use of calcineurin inhibitors (CNI) like cyclosporine A.
Katharina Huenges   +3 more
doaj   +1 more source

Defining a Methylation Signature Associated With Operational Tolerance in Kidney Transplant Recipients

open access: yesFrontiers in Immunology, 2021
Operational tolerance after kidney transplantation is defined as stable graft acceptance without the need for immunosuppression therapy. However, it is not clear which cellular and molecular pathways are driving tolerance in these patients.
Ramon M. Rodriguez   +24 more
doaj   +1 more source

Acceptance or rejection of biological restoration: An educational interventional study

open access: yesJournal of Family Medicine and Primary Care, 2020
Background: The quest for an ideal restorative material has led to the discovery of biological restoration that is, the use of natural tooth as a restorative material.
Dhanu G Rao   +6 more
doaj   +1 more source

Nanoparticle Platforms for Antigen-Specific Immune Tolerance

open access: yesFrontiers in Immunology, 2020
Innovative approaches in nanoparticle design have facilitated the creation of new formulations of nanoparticles that are capable of selectively calibrating the immune response.
Edward B. Thorp   +4 more
doaj   +1 more source

Tacrolimus Intrapatient Variability After Switching From Immediate or Prolonged-Release to Extended-Release Formulation, After an Organ Transplantation

open access: yesFrontiers in Pharmacology, 2021
Background and Purpose: Several formulations of tacrolimus are available, but evidence of the benefit of changing to the most recent formulations is lacking. Tacrolimus intra-patient variability (tacrolimus IPV) is an emerging risk factor associated with
Arnaud Del Bello   +11 more
doaj   +1 more source

The rejection game

open access: yesMind & Language, 2023
We introduce the rejection game, designed to formalize the interaction between interlocutors in a Stalnakerian conversation: a speaker who asserts something and a listener who may accept or reject. The rejection game is similar to other signalling games known to the literature in economics and biology.
Incurvati, Luca, Sbardolini, Giorgio
openaire   +4 more sources

Proteomics for Biomarker Discovery for Diagnosis and Prognosis of Kidney Transplantation Rejection

open access: yesProteomes, 2022
Renal transplantation is currently the treatment of choice for end-stage kidney disease, enabling a quality of life superior to dialysis. Despite this, all transplanted patients are at risk of allograft rejection processes. The gold-standard diagnosis of
Luís M. Ramalhete   +3 more
doaj   +1 more source

Identification of common blood gene signatures for the diagnosis of renal and cardiac acute allograft rejection. [PDF]

open access: yes, 2013
To test, whether 10 genes, diagnostic of renal allograft rejection in blood, are able to diagnose and predict cardiac allograft rejection, we analyzed 250 blood samples from heart transplant recipients with and without acute rejection (AR) and with ...
Hsieh, Szu-Chuan   +9 more
core   +5 more sources

Pediatric heart transplantation: how to manage problems affecting long-term outcomes? [PDF]

open access: yesClinical and Experimental Pediatrics, 2021
Since the initial International Society of Heart Lung Transplantation registry was published in 1982, the number of pediatric heart transplantations has increased markedly, reaching a steady state of 500–550 transplantation annually and occupying up to ...
Young Hwue Kim
doaj   +1 more source

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