Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Effects of rejection intensity and rejection sensitivity on social approach behavior in women.
PLoS ONE, 2020 ObjectivePerceived rejection plays an important role for mental health and social integration. This study investigated the impact of rejection intensity and rejection sensitivity on social approach behavior.Method121 female participants were randomly ...
Violetta K Schaan +4 more
doaj +1 more source
Are there negative cycles of peer victimization and rejection sensitivity? Testing ri-CLPMs in two longitudinal samples of young adolescents. [PDF]
Dev Psychopathol, 2023 This study's aim was to examine whether there are negative increasing cycles of peer victimization and rejection sensitivity over time. Drawing from Social Information Processing Theory, we hypothesized that victimization leads to higher levels of ...
Kellij S +5 more
europepmc +2 more sources
Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
Molecular Oncology, EarlyView.We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source
Ethnically-based rejection sensitivity and academic achievement: The danger of retracting into one’s heritage culture [PDF]
, 2014 This study examined the relation between ethnically based rejection sensitivity and academic achievement in a sample of 936 immigrant students in Germany and Switzerland. The theory of race-based rejection sensitivity that originated in North America was
Morf, Carolyn C. +2 more
core +1 more source
Rejection sensitivity and emotions
, 2023 Research on rejection sensitivity, daily rejection experiences and regulation of negative ...
Dominik Schoebi, Marianne Richter
core +1 more source
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
FEBS Open Bio, EarlyView.Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
Friendship quantity and quality as predictors of rejection sensitivity in adolescents [PDF]
Psychology and its Contexts, 2014 The current study examines friendship quality and quantity as unique predictors of rejection sensitivity in adolescents. The purpose of the study was to analyze whether the unique contributions of friendship quality and quantity differ in adolescent boys
Gabriela Šeboková, Marta Popelková
doaj
Criteria for diagnosis of humoral rejection using the method of 2D-speckle-tracking echocardiography
Вестник трансплантологии и искусственных органов, 2019 Aim: to identify predictors of humoral rejection at different stages using non-invasive methods of 2D-speckletracking echocardiography, to determine the correlation with immunological changes.Materials and methods. The study was conducted on the basis of
L. K. Tkhatl +3 more
doaj +1 more source
Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi +8 more
wiley +1 more source