Microstructural and Chemical Rejuvenation of a Ni-Based Superalloy [PDF]
, 2016 Zhiqi Yao +3 more
openalex +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Preparation and Performance Characterization of Warm‐Mix Rejuvenated Bioasphalt [PDF]
, 2020 Zhu Zhang +4 more
openalex +1 more source
Molecular Oncology, EarlyView.This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source
The Effect of Pressure-Promoted Thermal Rejuvenation on the Fracture Energy of Metallic Glasses
, 2021 H. Li, Zhen-Dong Sha
openalex +1 more source
Project Rejuvenation: A Time Tested 1 St Year Machine Tool Project [PDF]
, 2020 Harvey Svec, Harriet Svec
openalex +1 more source
LncRNA LYPLAL1-AS1 rejuvenates human adipose-derived mesenchymal stem cell senescence via transcriptional MIRLET7B inactivation [PDF]
, 2022 Yanlei Yang +7 more
openalex +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Teaching old mice new tricks: the utility of aged mouse models of C. difficile infection to study pathogenesis and rejuvenate immune response [PDF]
, 2021 Jae Hyun Shin +2 more
openalex +1 more source