Results 311 to 320 of about 160,770 (374)

Snakes and Ladders: A technological approach to tool maintenance byproducts using module flake categories. [PDF]

J Archaeol Method Theory
Nora D, Malinsky-Buller A, Gasparyan B, Petrosyan A, Frahm E.   +4 more
europepmc   +1 more source

Clonal succession after prolonged antiretroviral therapy rejuvenates CD8+ T cell responses against HIV-1

Eoghann White, Laura Papagno, Assia Samri, Kenji Sugata, Boris P. Hejblum, Amy R. Henry, Daniel C. Rogan, Samuel Darko, Patrícia Recordon-Pinson, Yasmine Dudoit, Sian Llewellyn‐Lacey, Lisa A. Chakrabarti, Florence Buseyne, Stephen A. Migueles, David A. Price, Marie-Aline Andreola, Yorifumi Satou, Rodolphe Thiébaut, Christine Katlama, Brigitte Autran, Daniel C. Douek, Victor Appay   +21 more
openalex   +2 more sources

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Erratum for the Research Article "Heterochronic parabiosis uncovers AdipoR1 as a critical player in retinal rejuvenation" by Y. Liu <i>et al</i>.

Sci Adv
europepmc   +1 more source

Construction of biomimetic gradient-structured cartilage organoids and mechanistic study of their application for cartilage rejuvenation. [PDF]

Bioact Mater
Miao X, Kong K, Rong K, Song Q, Guo T, Zhang C, Wu Q, Zhai Z, Sun Y, Gan Y, Xiang M, Dai K, Atala A, Lu Z.   +13 more
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Effectiveness of regenerative medicine for skin lightening and rejuvenation: a systematic review of extracellular vesicles and conditioned media. [PDF]

Stem Cell Res Ther
Jafarzadeh A, Hoseini SS, Behrangi E, Roohaninasab M, Goodarzi A.   +4 more
europepmc   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

Effects of Autologous Blood-Derived Extracellular Vesicles on Skin Regeneration and Anti-Aging: A Clinical Study. [PDF]

J Cosmet Dermatol
Kang H, Kim JH, Cho Y, Go D, Park J, Kim HG, Park S.   +6 more
europepmc   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source