Results 81 to 90 of about 3,383 (308)
Materials & DesignThe regeneration of asphalt pavements is essential for advancing green, circular, and sustainable transport infrastructure. A major challenge lies in the reverse design of rejuvenators tailored to the aging mechanisms of bitumen, particularly in ...
Liang He +3 more
doaj +1 more source
Self-healing composites: A review [PDF]
, 2015 Self-healing composites are composite materials capable of automatic recovery when damaged. They are inspired by biological systems such as the human skin which are naturally able to heal themselves.
Ji, Chunqian +2 more
core +2 more sources
T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities
Advanced Science, EarlyView.T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu +7 more
wiley +1 more source
Developments in the Built EnvironmentRejuvenating agents have been widely applied to recover the performance of aged asphalt. However, effective methods for evaluating their performance remain insufficient. To fill this research gap, three types of rejuvenators were selected as case studies
Qiqi Zhan +6 more
doaj +1 more source
Bacterial Outer Membrane Vesicles in Potentiating Cancer Vaccines: Progress and Prospects
Advanced Science, EarlyView.Bacterial outer membrane vesicles (OMVs) have emerged as versatile platforms for cancer vaccine development owing to their intrinsic immunostimulatory properties and high engineering flexibility. This review summarizes OMV biology, immune mechanisms, and engineering strategies that enhance vaccine efficacy, discusses key translational challenges, and ...
Jiabeini Zhang +9 more
wiley +1 more source
Stiffness modulus properties of hot mix asphalt containing waste engine oil [PDF]
, 2016 This study presents the effect of waste engine oil (WEO) on the mechanical properties of hot mix asphalt mixtures. It was added into mixture at 0%, 3%, 5%, 7%, 10% and 15% by weight of binder.
Abdullah, M. E. +7 more
core
Development‐based In Vivo Bioreactor Strategy for Challenging Senescent Bone Reconstruction
Advanced Science, EarlyView.We present a development‐based in vivo bioreactor strategy to generate rejuvenated bone grafts (vBR‐Bone) within aged hosts. By enclosing vBR‐Bone fragments within an asymmetric biomimetic periosteum, segmental femoral defects in aged mice were successfully repaired within 6 weeks. Mechanistically, the multifactors of vBR‐Bone reconstitute a remodeling
Wenchao Zhang +9 more
wiley +1 more source
Advanced Science, EarlyView.Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang +6 more
wiley +1 more source
BuildingsCurrently, there is limited research on the utilization of spent coffee grounds (SCG) in asphalt pavement. This study explores using SCG as a novel rejuvenator together with waste cooking oil (WCO) to enhance the performance of aged asphalt (AA).
Ruipeng Zhu, Chunhua Hu
doaj +1 more source
Advanced Science, EarlyView.This work identifies M1 macrophage‐mediated inflammation as a key driver of BMSC senescence and bone microstructural deterioration at the enthesis. A tissue‐adhesive hydrogel delivering senomorphic small extracellular vesicles suppresses this inflammatory‐senescent cascade and enhances BMSC resilience by inhibiting the cGAS‐STING‐NF‐κB pathway.
Lingzhi Kong +8 more
wiley +1 more source