Liver‐specific lncRNAs associated with liver cancers
Long non‐coding RNAs (lncRNAs) are regulatory molecules with various functions. They are more tissue‐specific than proteins and can be used as potential biomarkers, particularly in cancer diagnostics and prognosis. In this review, we have systematically compiled all lncRNAs with exclusive expression in the human liver, verified their liver specificity ...
Olga Y. Burenina+3 more
wiley +1 more source
Medical Cannabis Library: development of a curated database for research articles on cannabis therapeutic activity. [PDF]
Rodin D, Maizels Y, Koman I.
europepmc +1 more source
The E3 ubiquitin ligase, RNF219, suppresses CNOT6L expression to exhibit antiproliferative activity
We identified RNF219 as a CCR4‐NOT complex‐interacting E3 ubiquitin ligase that targets the CCR4‐NOT subunit CNOT6L for ubiquitination. RNF219 directly binds to the DUF3819 domain of CNOT1 through its putative α‐helix spanning amino acids 521–542. Our findings also suggest that antiproliferative activity of RNF219 is at least partially mediated by ...
Shou Soeda+9 more
wiley +1 more source
Towards a standardised methodology of radiation damage defect distributions for microstructure evolution models. [PDF]
Gutiérrez-Camacho AC+2 more
europepmc +1 more source
TTT and R2TP chaperone complexes are required for the assembly and activation of mTORC1. WAC directly interacts with components of TTT, R2TP, and mTORC1, and these interactions are affected by the availability of glucose and glutamine, correlating with changes in mTORC1 activity.
Sofía Cabezudo+11 more
wiley +1 more source
MilkOligoCorpus: A semantically annotated resource for knowledge extraction on mammalian milk oligosaccharides. [PDF]
Rumeau M+9 more
europepmc +1 more source
A note on estimating the cardinality of the projection of a database relation [PDF]
Ravi Mukkamala, Sushil Jajodia
openalex +1 more source
Most autophagic cell death studies lack evidence of causality
Of 104 studies claiming autophagic cell death (ACD), only 13 demonstrated both causality and exclusion of apoptosis to confirm true ACD. Most studies relied on correlation‐level data or measured autophagy in isolation, revealing pervasive methodological shortcomings.
Ali Burak Özkaya, Yasmin Ghaseminejad
wiley +1 more source
Enhancing biomedical relation extraction through data-centric and preprocessing-robust ensemble learning approach. [PDF]
Meesawad W+5 more
europepmc +1 more source
Relation of childhood gastrointestinal disorders to autism: nested case-control study using data from the UK General Practice Research Database [PDF]
Corri Black
openalex +1 more source