Results 201 to 210 of about 6,545,298 (346)

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Creating an Interactive Web Interface for Networks Stored in Knowledge Graph Databases. [PDF]

Curr Protoc
Evangelista JE, Lutsky AD, Byrd AI, Clarke DJB, Prabhakaran A, Jenkins SL, Ma'ayan A.   +6 more
europepmc   +1 more source

Executive Agreements Database, Statement Regarding Agreement Between The United States Patent and Trademark Office and The International Bureau of the World Intellectual Property Organization In Relation to the Functioning of the United States Patent and Trademark Office As and International Searching Authority and International Preliminary Examining Authority Under The Patent Cooperation Treaty Signed At Geneva October 1, 1997

, 1997
Oona A. Hathaway, Curtis A. Bradley, Jack L. Goldsmith   +2 more
openalex   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

RBP2GO 2.0: Integrating disease associations and sequence features to explore RNA-binding protein functions. [PDF]

Nucleic Acids Res
Cantarella S, Neffe J, Hermes M, Rauscher F, Schwarz R, Jaisankar P, Schäfer E, Caudron-Herger M.   +7 more
europepmc   +1 more source

Plausibility of Databases and the Relation to Imputation Methods

, 2008
Heinrich Fritz, Peter Filzmoser
openalex   +1 more source

Short-term blood pressure variability in relation to outcome in the International Database of Ambulatory blood pressure in relation to Cardiovascular Outcome (IDACO)

, 2011
Katarzyna Stolarz‐Skrzypek, Lutgarde Thijs, Yan Li, Tine W. Hansen, José Boggia, Tatiana Kuznetsova, Masahiro Kikuya, Gladys E. Maestre, Luis J. Mena, Kalina Kawecka−Jaszcz, Jan A. Staessen   +10 more
openalex   +2 more sources

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Diversity of FAAL enzymes and prediction of their substrate specificity using FAALPred. [PDF]

Protein Sci
Liong A, Pereira LM, Leão PN.
europepmc   +1 more source