Durable B‐Cell Impairment While Sparing IgA B Cells After Ocrelizumab Therapy in Multiple Sclerosis
ABSTRACT Objectives Ocrelizumab (OCR), a humanized anti‐CD20 monoclonal antibody, is highly efficient in relapsing–remitting multiple sclerosis (RR‐MS). We assessed early cellular B‐cell profiles in patients prior to OCR treatment, on OCR treatment, and after 15 months of therapy discontinuation.
Alexandra Garcia+20 more
wiley +1 more source
Effectiveness of predictive scoring systems in predicting mortality in relation to baseline kidney function in adult intensive care unit patients: a systematic review protocol. [PDF]
El Wadia H+10 more
europepmc +1 more source
Attenuation Relation for Near Field Shallow Crustal Earthquakes Using NGA-West Database with Mixed-Effect Model in Comparison with Attenuation Relations for Iran [PDF]
Alirez Shokran Neam, Touraj Taghikhany
openalex +1 more source
ABSTRACT Purpose This study aimed to explore the association between quantitative shape irregularity and density heterogeneity of hematomas and hematoma expansion (HE) for intracerebral hemorrhage (ICH) patients. Methods This cohort study included patients arriving within 24 h of symptom onset between August 2021 and July 2022 as the derivation cohort ...
Zeqiang Ji+11 more
wiley +1 more source
Changes in health insurance status and mortality in patients with acute heart failure. [PDF]
Viganego F+3 more
europepmc +1 more source
ABSTRACT Objective We aimed to investigate the comparative effectiveness of standard versus personalized extended interval dosing of anti‐CD20 therapy on clinical and sub‐clinical outcomes in multiple sclerosis. Methods Clinical information was collected prospectively on Research Electronic Data Capture.
Nabil K. El Ayoubi+6 more
wiley +1 more source
ERNIE-UIE: Advancing information extraction in Chinese medical knowledge graph. [PDF]
Li B+5 more
europepmc +1 more source
Rationale for Increasing Oncological Vigilance in Relation to Clinical Findings in Accessory Parotid Gland—Observations Based on 2192 Cases of the Polish Salivary Network Database [PDF]
Małgorzata Wierzbicka+14 more
openalex +1 more source
ABSTRACT Objective To identify metabolic patterns in the brain and musculoskeletal system of stiff person syndrome spectrum disorders (SPSD) patients over time using PET imaging and evaluate the impact of immune therapy on metabolic activity as a surrogate for treatment response.
Munther M. Queisi+4 more
wiley +1 more source