Results 141 to 150 of about 17,457,237 (334)

The IRG mouse: A two‐color fluorescent reporter for assessing Cre‐mediated recombination and imaging complex cellular relationships in situ [PDF]

, 2008
Rita De Gasperi, Anne B. Rocher, Miguel A. Gama Sosa, Susan L. Wearne, Gissel M. Perez, Victor L. Friedrich, Patrick R. Hof, Gregory A. Elder   +7 more
openalex   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

The relationship between histological differentiation and disease recurrence of primary oral squamous cell carcinoma

, 2017
R Padma, A. Kalaivani, Sivapatham Sundaresan, Paulraj Sathish   +3 more
openalex   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Understanding Structure-Performance Relationships of Coox/Ceo2 Catalysts for No Catalytic Oxidation: Facet Tailoring and Bimetallic Interface Designing

, 2023
Xiaomin Cheng, Yiqi Liu, Lubin Yang, Yongzheng Zhang, Cheng Ma, Xuan Meng, Xu Jing, Jitong Wang, Wenming Qiao   +8 more
openalex   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Speciation of Metal Complexes of Medicinal Interest: Relationship between Solution Equilibria and Pharmaceutical Properties

, 2018
Tamás Kiss, Éva A. Enyedy, Tamás Jakusch, Orsolya Dömötör   +3 more
openalex   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Design and Synthesis of Pleuromutilin Derivatives as Antibacterial Agents Using Quantitative Structure–Activity Relationship Model [PDF]

Jiaming Zhang, Qinqin Liu, Haoxia Zhao, Guiyu Li, Yunpeng Yi, Ruofeng Shang   +5 more
openalex   +1 more source

Newborn Behavioral Observation, maternal stress, depressive symptoms and the mother-infant relationship: Results from the Northern Babies Longitudinal Study (NorBaby). [PDF]

, 2020
Ragnhild Sørensen Høifødt, Dag Nordahl, Inger Pauline Landsem, Gábor Csifcsák, Agnes Bohne, Gerit Pfuhl, Kamilla Rognmo, Hanne Cecilie Braarud, Arnold Goksøyr, Vibeke Moe, Kari Slinning, Catharina Elisabeth Arfwedson Wang   +11 more
openalex   +1 more source