Results 141 to 150 of about 7,444,218 (259)

Single‐Nucleus RNA Sequencing Identifies CREM as a Brake on Myofiber Hypertrophy in Chickens

open access: yesAdvanced Science, EarlyView.
Single‐nucleus RNA sequencing on 91 144 nuclei from postnatal chicken pectoralis major between fast‐growing broilers (FG) and slow‐growing layers (SG) identifies the transcriptional factor CREM as a novel brake of myofiber hypertrophy. Mechanistically, functional validation experiments confirm that CREM activates the promoter of JUN and CREM deletion ...
Shuang Gu   +12 more
wiley   +1 more source

The Structural Relationship between Current and Capital Account Balance in India: A Time Series Analysis [PDF]

open access: yes
The long run relationship between current account balance (CAB) and capital account balance (KAB) and the repercussions of capital account convertibility (KAC) on growth process of a country is a much debated issue. In particular, in the aftermath of the
Sinha, Tanaya   +2 more
core  

Deep Learning for AD Risk Screening and Progression Prediction

open access: yesAdvanced Science, EarlyView.
A pretrained MRI‐based deep learning model generalizes from Western cohorts to an independent Chinese cohort, detects Alzheimer's disease with high sensitivity, and identifies elevated AD risk years before diagnosis. Its risk scores align with cognition and plasma biomarkers, and individualized brain risk maps uncover clinically distinct subtypes ...
Bin Lu   +12 more
wiley   +1 more source

Multiscale Freestanding Vertically Aligned CNT Heat Sink Enabling Multimodal Heat Dissipation by Conduction, Convection, and Radiation

open access: yesAdvanced Science, EarlyView.
This study demonstrates a vertically aligned CNT (VACNT)‐based heat sink. The nanoporous structure of the VACNT provides a large surface area for convective and radiative exchange, alongside axial conduction, enabling multimodal heat dissipation. Mounted on a CPU, the VACNT with a fin array pattern achieves a steady‐state temperature 6.7°C lower than a
Jongwon Park   +3 more
wiley   +1 more source

Job satisfaction and social capital in university teachers

open access: yesJournal of Health Management & Informatics, 2016
Introduction: Social capital is multidimensional and it is about the value of social networks and relations between people. Social capital refers to the relationships that forms the quality and quantity of the society’s social interactions.
Rita Rezaee, Parisa Nabeiei
doaj  

MAGI3 Acts as an Intestinal Epithelial Gatekeeper in Inflammation‐Associated Colorectal Cancer by Suppressing the STAT3‐CCL2 Axis and TAM‐Mediated Immunosuppression

open access: yesAdvanced Science, EarlyView.
Our study identifies MAGI3 as an intestinal epithelial gatekeeper that restrains inflammation‐associated colorectal tumorigenesis but is itself suppressed under highly inflammatory conditions. MAGI3 deficiency activates the STAT3‐CCL2 signaling, thereby promoting TAM‐mediated immunosuppression and inflammation‐associated colorectal tumor progression ...
Yumeng Yang   +12 more
wiley   +1 more source

Single‐Cell Map of Early Lung Adenocarcinoma Uncovers Invasion‐Associated Tertiary Lymphoid Structures

open access: yesAdvanced Science, EarlyView.
Early thoracic lesions are already heavily infiltrated by immune cells, yet these infiltrates largely consist of bystander T lymphocytes within an immunosuppressive microenvironment. Pathological invasion is strikingly associated with the neogenesis of T/B cell‐rich TLSs that predominantly remain immature.
Pengfei Ma   +20 more
wiley   +1 more source

Inequality, Human Capital and Development: Making the Theory Face the Facts [PDF]

open access: yes
Recent theoretical contributions assert that income inequality impacts negatively human capital accumulation, and consequently long-run growth. Galor and Zeira (1993) show that such a relationship works primarily through financial constraints, while de ...
Razak, Nor Azam Abdul   +1 more
core  

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