Results 71 to 80 of about 1,836,012 (321)

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Document-level Relation Extraction Based on Multi-relation View Axial Attention [PDF]

Jisuanji kexue
Document-level relationship extraction aims to extract relationships between multiple entities from documents.To address the limited multi-hop reasoning capacity of existing methods for establishing connections between entities with different ...
WU Hao, ZHOU Gang, LU Jicang, LIU Hongbo, CHEN Jing
doaj   +1 more source

Exact nonclassical symmetry solutions of Arrhenius reaction-diffusion

, 2015
Exact solutions for nonlinear Arrhenius reaction-diffusion are constructed in $n$ dimensions. A single relationship between nonlinear diffusivity and the nonlinear reaction term leads to a nonclassical Lie symmetry whose invariant solutions have a heat ...
Bradshaw-Hajek, B. H., Broadbridge, P., Triadis, D.   +2 more
core   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Remote supervised relationship extraction method of clustering for knowledge graph in aviation field

Intelligent Systems with Applications
In the process of building domain knowledge graph, the result of relationship extraction between entities is an important guarantee of the quality of the graph.
Jiayi Qu, Jintao Wang, Zuyi Zhao, Xingguo Chen   +3 more
doaj   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Automatic relationship extraction from agricultural text for ontology construction

Information Processing in Agriculture, 2018
In the present era of Big Data the demand for developing efficient information processing techniques for different applications is expanding steadily. One such possible application is automatic creation of ontology.
Neha Kaushik, Niladri Chatterjee
doaj   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Extracting Family Relationship Networks from Novels

, 2014
We present an approach to the extraction of family relations from literary narrative, which incorporates a technique for utterance attribution proposed recently by Elson and McKeown (2010). In our work this technique is used in combination with the detection of vocatives - the explicit forms of address used by the characters in a novel.
Makazhanov, Aibek, Barbosa, Denilson, Kondrak, Grzegorz   +2 more
openaire   +2 more sources

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source