An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Effects of market orientation on farmer resilience and dairy farm performance in emerging economy
The focal point of this study was determining the effect of market orientation on farm performance as moderated by farmer resilience in the volatile dairy sector of an emerging country, Kenya.
Dickson Otieno Okello, Fahad Juma Luttah
doaj +1 more source
Market Orientation, Customer Selectivity and Firm Performance [PDF]
Market orientation is a well-known construct in the marketing literature. One reason for the extensive research on market orientation is that it is seen as the operationalization of the marketing concept itself.
Khan, Aamir
core
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Relationship and innovation orientation in a business-to-business context
Market orientation and innovation orientation, including their relationship with firm performance, are well-debated in prevailing marketing literature. Interestingly, relationship orientation, as an extension of market orientation, is yet to be subjected
G. Human, P. Naudé
doaj +1 more source
Personality and religious orientation : shifting sands or firm foundations? [PDF]
Beit-Hallami and Argyle (1997) concluded that individual differences in religiosity are inversely related to psychoticism but independent of extraversion and neuroticism.
Francis, Leslie J.
core +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
The Effect of Achievement Goal Orientation on the Self-management of College Judo Athletes [PDF]
OBJECTIVES Primary purpose of current research was to examine effect of goal orientation tendency on self control. METHODS Among 2018 college athlets of Korea Judo Association, participants were recruited through convinence sampling. Except for insincere
Sungbae Park
doaj +1 more source
Entrepreneurial orientation and the franchise system: organisational antecedents and performance outcomes [PDF]
Purpose – The purpose of this paper is to understand the franchisor's perception of the role of entrepreneurial strategic orientation (EO) – innovative, risk-taking, and proactive actions – within the special case of franchised firms, given the opposing ...
Dada, O.L. +4 more
core +1 more source

