Results 91 to 100 of about 9,297,996 (306)

Baianos e paulistas: duas "escolas" de relações raciais? Baianos and paulistas, are there two "schools"of racial relationships?

Tempo Social, 1999
Os estudos de relações raciais realizados no Brasil entre 1937 e 1956 são muitas vezes invocados para respaldar a opinião de que existem diferenças regionais na situação racial brasileira ou de que diferentes escolas regionais interpretaram ...
Antônio Sérgio Alfredo Guimarães
doaj   +1 more source

Webs of "Wirkung": Modelling the interconnectedness of classification schemes [PDF]

, 2014
This paper explores relationships between different classification schemes. It suggests how these relationships could be considered part of the reception of a scheme, in particular as an aspect of its "Wirkung".
Lee, D.
core  

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Fiduciary relationships

Current Sociology
Although fiduciary relationships have a long tradition in Hammurabic, Jewish or Islamic codifications, they were especially conceived and instituted by Roman civil (private) law to normatively address asymmetrical interindividual relationships in which a settlor or beneficiary has an interest in the performance of a certain action, but does not have ...
openaire   +2 more sources

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Ancient Rule Passage Regime Debates in the Turkish Straits: 1841 London Protocol

Turcology Research, 2022
İsmail KÖSE
doaj   +1 more source

Medical cannabis in Israel: a comprehensive review of trends and regulations, 2011–2025

Journal of Cannabis Research
Background Since its initial approval in 1992, medical cannabis (MC) in Israel has undergone extensive regulatory and structural transformation. This study aims to present the most comprehensive retrospective analysis to date of the evolving MC policy ...
Joshua Aviram
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Sequentially Functional And Asthetic Restoration Of Severe Dentin Dysplasia

International Dental Journal
Introduction: This case report introduced sequentially functional and aesthetic restoration on a patient with dentin dysplasia type II (DD-II) accompanied by severe tooth wear. Case description: An eight-year-old girl with severe tooth wear presented for
Xuemei Liu, Xu Chen
doaj   +1 more source