Results 101 to 110 of about 3,561,517 (306)

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Predicting relative efficiency of amide bond formation using multivariate linear regression. [PDF]

open access: yesProc Natl Acad Sci U S A, 2022
Haas BC   +4 more
europepmc   +1 more source

What Do We Know About the Economic Efficiency of Cooperatives: An Evaluative Survey [PDF]

open access: yes
A debate has arisen concerning the economic efficiency of cooperatives relative to other organizational forms. This paper discusses the efficiency concepts and economic theory relevant to the debate and then proceeds to study the empirical evidence.
Iskow, Julie, Sexton, Richard J.
core   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Selection indices for yield improvement in bread wheat (Triticum aestivum L.)

open access: yesElectronic Journal of Plant Breeding, 2020
The discriminant-function technique was used to construct selection indices in 48 genotypes of bread wheat (Triticum aestivum L.). Sixty-three selection indices involving grain yield per plant and its five components were constructed using the ...
S. G. P. Karthikeya Reddy and C. A. Babariya
doaj   +1 more source

Getting the Most Bang for the Buck: An Analysis of States’ Relative Efficiencies in Promoting the Birth of Small Firms [PDF]

open access: yes
Firm birth has recently been an important topic for many state governments. However, ways in which state governments can influence firm births are not obvious, and their efficiency in fostering firm births in comparison with their peers is even less so ...
Maria Marshall, Whitney Peake
core  

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Remotely sensed data controlled forest inventory concept

open access: yesEuropean Journal of Remote Sensing, 2018
Nowadays, the image of the forest in Germany is changing from monoculture areas to very mixed forests, where individual stands are no longer clearly visible.
Adelheid Wallner   +5 more
doaj   +1 more source

relative photonic efficiency

open access: yes
Citation: 'relative photonic efficiency' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.14084 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

Wage inequality and overeducation in a model with efficiency wages [PDF]

open access: yes
This paper shows that the existence and persistence of ‘overeducation’ can be explained by an extension of the efficiency wage model. When calibrated to fit the amounts of overeducation found in most empirical studies, the model implies that both the ...
Peter Skott
core  

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