Results 181 to 190 of about 3,561,517 (306)
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Comparison of relative efficiency of genomic SSR and EST-SSR markers in estimating genetic diversity in sugarcane. [PDF]
3 Biotech, 2018 Parthiban S +2 more
europepmc +1 more source
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Correction to 'The relative efficiency of modular and non-modular networks of different size'. [PDF]
Proc Biol Sci, 2015 Tosh CR, McNally L.
europepmc +1 more source
Relative efficiency between two tests
, 2016 The choice of the primary endpoint is an important issue when designing a clinical trial. The motivation of this Master thesis is to develop a methodology based on the Asymptotic Relative Efficiency (ARE) that discerns between a compound of binary variables or one of its elements as the primary response of the trial.
openaire +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Relative efficiency of unequal versus equal cluster sizes in cluster randomized trials using generalized estimating equation models. [PDF]
Biom J, 2018 Liu J, Colditz GA.
europepmc +1 more source
Relative efficiencies of reduction machines
Relative efficiencies of reduction machinesRelative efficiency of the reduction of lambda-terms and that of combinatory expressions are compared when they represent recursive programs belonging to the linear branched recursion schema in Strong [7]. The terms and the expressions are extended versions by introducing constants and some primitive operations on them, and all of them are reduced by ...
openaire
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
The relative efficiency of modular and non-modular networks of different size. [PDF]
Proc Biol Sci, 2015 Tosh CR, McNally L.
europepmc +1 more source