Results 231 to 240 of about 3,561,517 (306)

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Genetic evaluation of growth rate and efficiency-related traits in Menz sheep. [PDF]

PLoS One
Bisrat A, Besufkad S, Abebe A, Goshme S, Abebe A, Zewdie T, Areaya A, Tesema Z, Demis C, Yitagesu E, Wondifra Y, Asfaw T, Alemnew E, Gizaw S, Getachew T, Rischkowsky B, Rekik M, Belay B, Haile A.   +18 more
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Effect of weight-based fertigation on physiology, gas exchange and yield of soilless cucumber and capsicum. [PDF]

Sci Rep
Randhe RD, Hasan M, Singh DK, Naresh Kumar S, Kumar P, Alam W, Pandey R, Kumar M, Waghaye AM.   +8 more
europepmc   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Log-ratio type estimation for the finite population mean under simple random sampling without replacement with theory, simulation and application. [PDF]

Sci Rep
Shakoor F, Atif M, Ali H, Alshammari AO, Himmat B, Kefi K.   +5 more
europepmc   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Compact bacterial recombination complexes drive efficient kilobase-scale knock-in in mammalian cells. [PDF]

Nucleic Acids Res
Luo Y, Jiang Q, Qu Y, Li W, Liu R, Zhu Y, Xie Y, Jiang C, Chen C, Cong L, Han F, Bao J, Wang C.   +12 more
europepmc   +1 more source

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

FEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc, Blaž Stres, Mirica Karlovits, Igor Karlovits, Petra Jerič, Ondrej Panák, Anja Verbič, Blaž Likozar, Uroš Novak   +8 more
wiley   +1 more source

Enriched Acoustic Environment Therapy (EAE): A Cost-Effective and Feasible Alternative to Tinnitus Retraining Therapy (TRT). [PDF]

Healthcare (Basel)
Fernández-Ledesma M, Sanz-Fernández R, Cuesta M, Cobo P.   +3 more
europepmc   +1 more source