Results 111 to 120 of about 3,054,956 (233)
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Relative Entropy, Gaussian Concentration and Uniqueness of Equilibrium States. [PDF]
Entropy (Basel), 2022 Chazottes JR, Redig F.
europepmc +1 more source
Molecular Oncology, EarlyView.Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso +5 more
wiley +1 more source
Entropy-based semi-fragile watermarking of remote sensing images in the wavelet domain
, 2019 This article presents a semi-fragile image tampering detection method for multi-band images. In the proposed scheme, a mark is embedded into remote sensing images, which have multiple frequential values for each pixel, applying tree-structured vector ...
Serra Ruiz, Jordi +5 more
core +1 more source
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
Quantifying Information without Entropy: Identifying Intermittent Disturbances in Dynamical Systems
, 2020 A system’s response to disturbances in an internal or external driving signal can be characterized as performing an implicit computation, where the dynamics of the system are a manifestation of its new state holding some memory about those disturbances.
Moreu, Fernando +2 more
core
Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer
Molecular Oncology, EarlyView.Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba +5 more
wiley +1 more source
Bounds for Kullback-Leibler divergence
Electronic Journal of Differential Equations, 2016 Entropy, conditional entropy and mutual information for discrete-valued random variables play important roles in the information theory. The purpose of this paper is to present new bounds for relative entropy $D(p||q)$ of two probability distributions
Pantelimon G. Popescu +3 more
doaj
Research on the Robustness of the Chinese Input-Output Network Based on Relative Entropy Theory. [PDF]
Entropy (Basel), 2022 Li W, Wang A, Xing W.
europepmc +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source