Results 141 to 150 of about 5,228,188 (305)

Sexual maturity and reproductive period of the swimming blue crab Callinectes danae Smith, 1869 (Brachyura: Portunidae) from Guaratuba Bay, Paraná State, southern Brazil

open access: yesNauplius
This work aims to estimate the average size at the onset of morphological and physiological sexual maturity and the reproductive period of Callinectes danae.
Murilo Zanetti Marochi   +4 more
doaj  

Government expenditure and economic growth: Evidence from trivariate causality testing [PDF]

open access: yes
This paper seeks to examine if the relative size of government (measured as the share of total expenditure in GNP can be determined to Granger cause the rate of economic growth, or if the rate of economic growth can be determined to Granger cause the ...
George Vamvoukas, John Loizides
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

PHYSICAL AND HUMAN CAPITAL INVESTMENT: RELATIVE SUBSTITUTES IN THE ENDOGENOUS GROWTH PROCESS [PDF]

open access: yes
This paper aims at studying the interaction between growth of real output and human capital accumulation when education requires investment of physical resources.
Alexandra Rillaers, Jorge Durán
core  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Genome-wide association analysis to identify candidate genes for growth rate traits in Chinese endemic geese

open access: yesBMC Genomics
Background China has abundant resources of local goose breeds with significant differences in growth rates among breeds. These differences provide natural genetic materials for exploring key functional genes and molecular markers of growth traits.
Hongning Wang   +4 more
doaj   +1 more source

How important are capital and total factor productivity for economic growth? [PDF]

open access: yes
The authors examine the relative importance of the growth of physical and human capital and the growth of total factor productivity (TFP) using newly organized data on 145 countries that span more than one hundred years for twenty-four of these countries.
Gerald P. Dwyer, Jr.   +2 more
core  

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

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