Results 161 to 170 of about 5,228,188 (305)

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

The relative growth of subordinate functions.

open access: yesMichigan Mathematical Journal, 1971
Bogucki, Zbigniew, Waniurski, Józef
openaire   +3 more sources

A Demand-Supply Analysis of the Spanish Education Wage Premium in the 1980s and 1990s. [PDF]

open access: yes
We estimate the demand for education in Spain, and use the estimated demand curve to analyze whether the evolution of the education wage premium in the 1980s and 1990s can be explained by a demand-supply framework.
Manuel A. Hidalgo
core  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Condition factor and carapace width versus wet weight relationship in the swimming crab Callinectes danae Smith 1869 (Decapoda: Portunidae) at the Santa Cruz Channel, Pernambuco State, Brazil

open access: yesNauplius
The present work aims to study the size vs. weight relationship and the condition factor of a commercially important crab, Callinectes danae, from an estuarine complex located at Pernambuco State, Northeastern Brazil.
Marina de Sá Leitão Câmara de Araújo   +1 more
doaj  

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