Ti<sub>3</sub>C<sub>2</sub>T<sub>x</sub> (MXene) disrupts growth and development in <i>Daphnia magna</i> by suppressing related genes and inducing gut microbiome dysbiosis. [PDF]
Xiang Q, Wu Y, Li Y, Li S, Chang X.
europepmc +1 more source
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Putative transcription factor Skn7 is involved in cell wall formation, oxidative stress response, and hydrophobin gene expression in Pleurotus ostreatus. [PDF]
Izumi T +4 more
europepmc +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
Effects of letrozole supplementation on growth performance, blood indexes, ruminal fermentation parameters, and microbiome composition of <i>hu</i> lambs. [PDF]
Yang L +8 more
europepmc +1 more source
Overview of molecular signatures of senescence and associated resources: pros and cons
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
β<sub>2</sub>-adrenoceptor signaling in chondrocytes regulates long bone growth, bone homeostasis, and fracture healing in mice. [PDF]
Kuhn MR +8 more
europepmc +1 more source
Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source
Differential <i>in vitro</i> and <i>in vivo</i> responses of <i>Akkermansia muciniphila</i> to <i>Odontosoria biflora</i> (Kaulf.) C.Chr. [<i>Lindsaeaceae</i>] hexane extract in diet- and alloxan-induced BALB/c mice. [PDF]
Hamel Darbandi M, Dalmacio LMM.
europepmc +1 more source
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso +4 more
wiley +1 more source

