Results 111 to 120 of about 15,119,997 (287)
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
The Indian Journal of Agricultural SciencesAn experiment was conducted out during winter (rabi) seasons of 2021–22 and 2022–23 at the Research Farm of Maharana Pratap Univesity of Agriculture and Technology, Udaipur, Rajasthan to study the effect of nutrient management practices and sowing ...
ADARSH SHARMA +5 more
doaj +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
BMC Plant BiologyBackground Cannabis is a historically, culturally, and economically significant crop in human societies, owing to its versatile applications in both industry and medicine.
Mehdi Babaei +3 more
doaj +1 more source
Dynamic Modeling of Agricultural Fresh and Dry Biomass Under Variable Nutrient Supply
AgricultureData-driven empirical models, including those based on reaction kinetics, are well-regarded for their ability to make accurate predictions and uncover underlying relationships.
Andrew Sharkey +3 more
doaj +1 more source
The Optimum Growth Rate for Population Reconsidered [PDF]
This article gives exact general conditions for the existence of an interior optimum growth rate for population in the neoclassical two-generations-overlapping model.
Klaus Jaeger, Wolfgang Kuhle
core
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
, 1975 http://babel.hathitrust.org/cgi/pt?id=mdp.39015007423828;view=2up;ui=fullscreen#page/n0/mode ...
Symposium on Craniofacial Growth
core +2 more sources