Results 231 to 240 of about 3,761,115 (301)

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Rapid ice-marginal lake growth in Alaska driven by glacier retreat through bed overdeepenings. [PDF]

Proc Natl Acad Sci U S A
McGrath D, Sass L, Armstrong WH, Florentine C, McCoy SW.   +4 more
europepmc   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

The effect of environmental variation on stable coexistence of competitors: experimental evidence from zooplankton (<i>Daphnia magna</i> and <i>D. pulex</i>). [PDF]

J Plankton Res
Einum S, Burton T, Larsen SM, Rani V, Lee AM.   +4 more
europepmc   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

An Explicit Test of Kill the Winner: Protistan Grazing and Phage Lysis Differentially Impact Fast-Growing Bacterial Taxa in the Coastal Antarctic. [PDF]

Environ Microbiol
Connors E, Coker A, Wang GS, Zeigler L, Bowman JS.   +4 more
europepmc   +1 more source

Fluid and Neuroimaging Biomarkers in Microgliopathy Colony‐Stimulating Factor‐1 Receptor‐Related Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela, Madison Reeves, Karen Jansen‐West, Judith Dunmore, Yuping Song, Audrey Strongosky, Sunil Gandhi, Gilana Pikover, Matt Blurton‐Jones, Robert C. Spitale, Erik H. Middlebrooks, Leonard Petrucelli, Mercedes Prudencio, Zbigniew K. Wszolek   +13 more
wiley   +1 more source

Tracking Inter- and Intraspecific Bacterial Competition in Pairwise Assays Using a Transient Fluorescent Dye. [PDF]

Ecol Evol
Hoffmann J, Johannsen O, Becks L.
europepmc   +1 more source

Multilevel analysis of salt stress responses in sorghum during seed germination. [PDF]

Front Plant Sci
Wang HJ, Yu Y, Zhao Y, Wang H, Hu X, Ullah U, Yang B, Huang J, Chen K, Khan AH, Abbas W, Feng G, Kuerban Z.   +12 more
europepmc   +1 more source