Results 231 to 240 of about 4,168,743 (288)

Validation of a Cellular Imaging‐Based Method as a Potential Biomarker for SPG4 Hereditary Spastic Paraplegia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Hereditary Spastic Paraplegia (HSP) comprises a group of rare genetic diseases characterized by length‐dependent axonal degeneration of the corticospinal tracts and dorsal columns, whose main clinical feature is spastic gait. Pathogenic variants in the SPG4 gene cause Spastic Paraplegia Type 4 (SPG4‐HSP), the most common form of HSP.
Gaia Fattorini   +12 more
wiley   +1 more source

Progressive Parkinsonism in PPP2R5D‐Related Neurodevelopmental Disorder

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT PPP2R5D‐related neurodevelopmental disorder (Houge–Janssens syndrome type 1) is a rare autosomal dominant condition characterized by macrocephaly, intellectual disability, and epilepsy. Progressive parkinsonism is an emerging adult phenotype that neurologists should be aware of since timely genetic diagnosis opens the door to disease‐modifying
Katerina Bernardi   +6 more
wiley   +1 more source

Stage‐Dependent β‐Synuclein Links MRI and Cognitive Decline in Alzheimer's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Synaptic degeneration drives cognitive decline in Alzheimer's disease (AD), but synaptic biomarkers are scarce. Brain‐enriched β‐synuclein emerged as a synaptic damage marker. We investigated its diagnostic, prognostic, and structural correlates across the AD continuum.
Ulaş Ay   +15 more
wiley   +1 more source

Relative Motion [PDF]

open access: yes
Presentación para la asignatura "Orbital Dynamics" (18079)1. Introduction to relative motion in orbit 2. Dynamics of relative motion and formation flying 3. Linearized equations 4. Clohessy-Wiltshire equations 5.
Di Sotto, Emanuele, Zhou, Jiewei
core   +4 more sources
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Detection of relative and uniform motion

Journal of the Optical Society of America A, 2002
We measured the lowest velocity (velocity threshold) for discriminating motion direction in relative and uniform motion stimuli, varying the contrast and the spatial frequency of the stimulus gratings. The results showed significant differences in the effects of contrast and spatial frequency on the threshold, as well as on the absolute threshold level
Satoshi, Shioiri   +3 more
openaire   +2 more sources

RELATIVE MOTION. 3. SOME RELATIVE MOTION PROBLEMS IN AVIATION

1961
Abstract : This study was conducted for the purpose of exploring relative motion problems in a variety of pilot and navigator tasks. Field studies surveyed methods used by pilots to fly intercepts; analyzed the guidance of air-to-ground missiles; and identified relative motion problems in attitude and navigation displays including the ANIP display.
Hugh M. Bowen   +2 more
openaire   +1 more source

True Motion and Relative Motion

Journal of Navigation, 1966
1. Types of presentation. The choice of the method of presentation used by a radar operator is probably the most important of the various alternatives open to him for the most effective keeping of his watch, because they are all different, each has its advantages and limitations and one of them may be best suited to the circumstances and to the ...
openaire   +1 more source

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