Results 41 to 50 of about 433,317 (265)
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Facial motion perception in autism spectrum disorder and neurotypical controls [PDF]
This thesis was submitted for the degree of Doctor of Philosophy and was awarded by Brunel University LondonFacial motion provides an abundance of information necessary for mediating social communication.
Girges, Christine, Christine Girges
core
Geurten BRH, Kern R, Egelhaaf M. Species-Specific Flight Styles of Flies are Reflected in the Response Dynamics of a Homolog Motion-Sensitive Neuron. Frontiers in Integrative Neuroscience.
Egelhaaf, Martin +10 more
core +1 more source
Periodic Solutions of Nonlinear Relative Motion Satellites
The relative motion of an outline of the rendezvous problem has been studied by assuming that the chief satellite is in circular symmetric orbits. The legitimacy of perturbation techniques and nonlinear relative motion are investigated.
Elbaz I. Abouelmagd +3 more
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Egelhaaf M, Borst A, Reichardt W. Computational structure of a biological motion-detection system as revealed by local detector analysis in the fly's nervous system. Journal of the Optical Society of America, A: Optics, Image Science, and Vision.
Egelhaaf, M. +5 more
core +1 more source
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source

