Results 61 to 70 of about 1,830,137 (233)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Enrichments/Derichments of Root-Associated Bacteria Related to Plant Growth and Nutrition Caused by the Growth of an EPSPS-Transgenic Maize Line in the Field

Frontiers in Microbiology, 2019
During the past decades, the effects of the transgenic crops on soil microbial communities have aroused widespread interest of scientists, which was mainly related to the health and growth of plants.
Zhong-Ling Wen, Zhong-Ling Wen, Min-Kai Yang, Min-Kai Yang, Mei-Hang Du, Mei-Hang Du, Zhao-Zhao Zhong, Yun-Ting Lu, Yun-Ting Lu, Gu-Hao Wang, Xiao-Mei Hua, Aliya Fazal, Chun-Hua Mu, Shu-Feng Yan, Yan Zhen, Rong-Wu Yang, Jin-Liang Qi, Jin-Liang Qi, Zhi Hong, Gui-Hua Lu, Gui-Hua Lu, Yong-Hua Yang, Yong-Hua Yang   +22 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

On Schröder-Type Series Expansions for the Lambert W Function

AppliedMath
Schröder based series for the principal and negative one branches of the Lambert W function are defined; the series are generic and are in terms of an initial, arbitrary, approximating function.
Roy M. Howard
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

An advanced method of interpolation of short-focus electron beams boundary trajectories using higher-order root-polynomial functions and its comparative study

Sistemnì Doslìdženâ ta Informacìjnì Tehnologìï
The comparison of three advanced novel methods for estimating the boundary trajectory of electron beams propagated in ionized gas, including lower-order interpolation, self-connected interpolation, and extrapolation, as well as higher-order interpolation,
Igor Melnyk, Alina Pochynok, Mykhailo Skrypka   +2 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

An accurate relationship between frequency and amplitude to nonlinear oscillations

Journal of Taibah University for Science, 2018
A weighted global error minimization (WGEM) is proposed in this study. The goal is to improve the accuracy of the global error minimization (GEM) based on a weighting function.
M. K. Yazdi
doaj   +1 more source