Results 91 to 100 of about 16,613,458 (340)

Genetic Risk, Adherence to a Healthy Lifestyle, and Coronary Disease

open access: yesNew England Journal of Medicine, 2016
BACKGROUND Both genetic and lifestyle factors contribute to individual-level risk of coronary artery disease. The extent to which increased genetic risk can be offset by a healthy lifestyle is unknown.
A. Khera   +15 more
semanticscholar   +1 more source

Germline TP53 Mutations Causing Diamond–Blackfan Anemia: A French Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Diamond–Blackfan anemia is a rare congenital erythroblastopenia typically caused by mutations in ribosomal protein genes. Recently, gain‐of‐function mutations in TP53 have been identified as a novel cause of Diamond–Blackfan anemia. We report two French patients who both harbored a heterozygous TP53 deletion (NM_000546.5: c.1077delA; p ...
Rafael Moisan   +6 more
wiley   +1 more source

Association between Oral Cancer and Smokeless Tobacco Use in Rural Indian Men: A Prospective Cohort Study

open access: yesJournal of Pharmacy and Bioallied Sciences
Background: Smokeless tobacco (SLT) use, particularly gutka and khaini, is a significant public health concern in India, mainly in rural areas. This prospective cohort study aimed to investigate the association between SLT use and oral cancer incidence ...
Anuj Singh Parihar   +5 more
doaj   +1 more source

When do jumps matter for portfolio optimization? : [Version 29 April 2013] [PDF]

open access: yes, 2013
We consider the continuous-time portfolio optimization problem of an investor with constant relative risk aversion who maximizes expected utility of terminal wealth. The risky asset follows a jump-diffusion model with a diffusion state variable.
Ascheberg, Marius   +2 more
core   +1 more source

‘They Need to Hear You Say It’: Healthcare Professionals’ Perspectives on Barriers and Enablers to End‐of‐Life Discussions With Adolescents and Young Adults With Cancer

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT End‐of‐life conversations with adolescents and young adults (AYAs) with cancer rarely occur without the guidance of healthcare professionals. As a part of the ‘Difficult Discussions’ study, focused on palliative care and advance care planning discussions with AYAs with cancer, we investigated the factors that healthcare professionals identify ...
Justine Lee   +9 more
wiley   +1 more source

Relative risk of renal disease among people living with HIV: a systematic review and meta-analysis

open access: yesBMC Public Health, 2012
BackgroundAntiretroviral therapy (ART) has substantially decreased mortality and HIV-related morbidity. However, other morbidities appear to be more common among PLHIV than in the general population.
Fakhrul M Islam   +3 more
semanticscholar   +1 more source

Feasibility and Safety of High‐Dose Proton Re‐Irradiation in Recurrent Pediatric Central Nervous System Tumors: A Single‐Institution Retrospective Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Pediatric central nervous system (CNS) tumors often recur despite multimodality therapy. Although re‐irradiation (re‐RT) has historically been limited by concerns for severe late toxicities, modern techniques have renewed interest in this approach. Proton therapy provides dosimetric advantages that may enable curative re‐treatment with
Jin‐Ho Song   +15 more
wiley   +1 more source

RELATIVE AND ABSOLUTE RISK FORMAT IN ELICITING WILLINGNESS-TO-PAY FOR BEEF IRRADIATION [PDF]

open access: yes
The relationship between the valuation of reduced risk through irradiation and framing of risk information was determined using absolute and relative risk formats.
Fletcher, Stanley M.   +2 more
core   +1 more source

Ethnicity, Obesity, and Type 2 Diabetes of Adults in Urban Populations of Central America [PDF]

open access: yes, 2017
The purpose of this meta-analysis was to examine the impact of ethnicity and obesity as it relates to Type-2 Diabetes (T2D) in specific Central American countries. A meta-analysis was conducted to determine the association of ethnicity, obesity, and T2D.
Humphries, J. (James)   +3 more
core  

Labor Induction versus Expectant Management in Low-Risk Nulliparous Women

open access: yesNew England Journal of Medicine, 2018
Background The perinatal and maternal consequences of induction of labor at 39 weeks among low‐risk nulliparous women are uncertain. Methods In this multicenter trial, we randomly assigned low‐risk nulliparous women who were at 38 weeks 0 days to 38 ...
W. Grobman   +21 more
semanticscholar   +1 more source

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