FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Design and simulation of photonic crystal fiber for highly sensitive chemical sensing applications
Open EngineeringPhotonic crystal fibers (PCF) have demonstrated promising capabilities for liquid sensing applications owing to their distinctive optical properties. This work presents a numerical investigation of a PCF sensor optimized for discriminating water, ethanol,
Jebur Raed Sattar, Thaher Raad Hamdan
doaj +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Selection of indicators reporting response rate in pharmaceutical trials for systemic lupus erythematosus: preference and relative sensitivity. [PDF]
Lupus Sci Med, 2023 Tian J +6 more
europepmc +1 more source
Development of a sensitivity analysis technique for multiloop flight control systems [PDF]
This report presents the development and application of a sensitivity analysis technique for multiloop flight control systems. This analysis yields very useful information on the sensitivity of the relative-stability criteria of the control system, with ...
Downing, D. R. +2 more
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Relative sensitivity of duckweed Lemna minor and six algae to seven herbicides. [PDF]
J Pestic Sci, 2021 Ueda K, Nagai T.
europepmc +1 more source
ORKA: The Golden Kaon Experiment
, 2012 ORKA is a proposed experiment to measure the K+ -> pi+ nu nubar branching ratio with 5% precision using the Fermilab Main Injector high intensity proton source. The detector design is based on the BNL E787/E949 experiments, which detected seven candidate
Worcester, E. T.
core +1 more source
Rod sensitivity relative to cone sensitivity in retinitis pigmentosa.
Investigative ophthalmology & visual science, 1979 The present study evaluates rod sensitivity relative to cone sensitivity in retinitis pigmentosa patients. From perimetric measures of absolute thresholds to long- and short-wavelength stimuli, we find the results can be characterized in three different ways.
R W, Massof, D, Finkelstein
openaire +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source