Results 41 to 50 of about 1,674,742 (295)

Quantifying the overall added value of dynamical downscaling and the contribution from different spatial scales [PDF]

open access: yes, 2016
This study evaluates the added value in the representation of surface climate variables from\ud an ensemble of regional climate model (RCM) simulations by comparing the relative skill of the RCM\ud simulations and their driving data over a wide range of ...
Argüeso, Daniel   +4 more
core   +1 more source

Why and When Are Evidence‐Based Interventions Adopted in Paediatric Supportive Care? A Qualitative Exploration of the Determinants of Photobiomodulation Implementation

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Oral mucositis is a common and debilitating side effect of childhood cancer and stem cell transplant treatments. It affects the quality of life of children and young people (CYP) and places a strain on services. Photobiomodulation is recommended for oral mucositis prevention in international guidance but is poorly implemented in UK ...
Claudia Heggie   +4 more
wiley   +1 more source

Evaluation of TIEGCM based on GOCE neutral density

open access: yesFrontiers in Physics
The Thermosphere Ionosphere Electrodynamic General Circulation Model (TIEGCM), as one of the most advanced physical models of the Earth’s thermosphere and ionosphere, is not only widely used in scientific research, but also has essential reference value ...
Zheng Li   +7 more
doaj   +1 more source

A hierarchically blocked Jacobi SVD algorithm for single and multiple graphics processing units [PDF]

open access: yes, 2014
We present a hierarchically blocked one-sided Jacobi algorithm for the singular value decomposition (SVD), targeting both single and multiple graphics processing units (GPUs). The blocking structure reflects the levels of GPU's memory hierarchy.
Novaković, Vedran
core   +1 more source

Real‐World Pediatric Blinatumomab Administration: Access to Outpatient Care Delivery and Impact of a Hospital‐Dispensed Model

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Blinatumomab has been shown to be highly effective for patients with pediatric B‐ALL and has recently become standard of care therapy. Due to its past use in the clinical trial setting, there is limited information available about real‐world administration.
Katelyn Oranges   +12 more
wiley   +1 more source

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács   +8 more
wiley   +1 more source

Phenotype–environment mismatch in metapopulations—Implications for the maintenance of maladaptation at the regional scale

open access: yesEvolutionary Applications, 2019
Maladaptation is widespread in natural populations. However, maladaptation has most often been associated with absolute population decline in local habitats rather than on a spectrum of relative fitness variation that can assist natural populations in ...
Jorge Octavio Negrín Dastis   +3 more
doaj   +1 more source

Density Perturbations,Gravity Waves and the Cosmic Microwave Background

open access: yes, 1992
We asses the contribution to the observed large scale anisotropy of the cosmic microwave background radiation, arising from both gravity waves as well as adiabatic density perturbations, generated by a common inflationary mechanism in the early Universe.
Sahni, Varun, Souradeep, Tarun
core   +1 more source

First measurement of the 14N/15N ratio in the analogue of the Sun progenitor OMC-2 FIR4 [PDF]

open access: yes, 2017
We present a complete census of the 14N/15N isotopic ratio in the most abundant N-bearing molecules towards the cold envelope of the protocluster OMC-2 FIR4, the best known Sun progenitor.
Al-Edhari, Ali Jaber   +5 more
core   +4 more sources

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski   +9 more
wiley   +1 more source

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