Results 91 to 100 of about 437,604 (285)

Pulmonary Delivery of siRNA Anti‐TNFα‐loaded Lipid Nanoparticles for Rapid Recovery in Murine Acute Lung Injury

Advanced Healthcare Materials, EarlyView.
In a murine model of acute lung injury, pulmonary administration of lipid nanoparticles carrying TNFα siRNA enables targeted delivery to immune cells. The study emphasises the importance of optimizing LNP distribution and delivery timing to improve therapeutic outcomes and develop emergency therapies for lung hyperinflammation.
Qinglin Wang, Jihana Achour, Laila Emam, Younes Louaguenouni, Catherine Cailleau, Françoise Mercier‐Nomé, Séverine Domenichini, Claudine Delomenie, Sezen Gul, Juliette Vergnaud, Nicolas Tsapis, Arnaud Mansart, Djillali Annane, Francois Fay, Elias Fattal   +14 more
wiley   +1 more source

Inhalability and Bioactivity of Spray‐Dried versus Pressurized Gas eXpanded Liquid Technology‐Processed Yeast Beta‐Glucan Microparticles for Anti‐Fibrotic Therapies

Advanced Healthcare Materials, EarlyView.
PGXTEC) liquid technology is utilized to develop highly respirable yeast beta‐glucan (YBG) microparticles for the treatment of pulmonary fibrosis. Compared to conventionally processed spray‐dried YBG, PGXTEC‐YBG exhibits greatly improved aerodynamic properties, enhanced pro‐fibrotic macrophage uptake, and effective downregulation of pro‐fibrotic ...
Nate Dowdall, Safaa Naiel, Quan Zhou, Pareesa Ali, Tamana Rubina Yousof, Emily Wong, Ricardo Couto, Byron Yépez, Bernhard Seifried, Paul Moquin, Rod Rhem, Myrna Dolovich, Martin Rainer Kolb, Kjetil Ask, Todd Hoare   +14 more
wiley   +1 more source

Programmable Compliance in Small‐Diameter Vascular Grafts by Design of Melt‐Electrowritten Scaffold Architectures for In Situ Tissue Engineering

Advanced Healthcare Materials, EarlyView.
Small‐diameter vascular grafts with compliance tunable by design are fabricated via melt electrowriting. By controlling the winding angle of intertwined helical fibers, grafts with compliances matching those of human vessels, from veins to arteries, are realized. This holds the potential of avoiding a compliance mismatch, which has been identified as a
Kilian Maria Arthur Mueller, Christina Ahrens, Linda Grefen, Salma Mansi, Dario Arcuti, Elena De‐Juan‐Pardo, Felix Kur, Christian Hagl, Petra Mela   +8 more
wiley   +1 more source

Commensurating endomorphisms of acylindrically hyperbolic groups and applications

, 2016
We prove that the outer automorphism group $Out(G)$ is residually finite when the group $G$ is virtually compact special (in the sense of Haglund and Wise) or when $G$ is isomorphic to the fundamental group of some compact $3$-manifold.
Antolin, Yago, Minasyan, Ashot, Sisto, Alessandro   +2 more
core   +1 more source

Current Challenges in Hemostasis and Advances in Particle‐Assisted Styptic Devices

Advanced Healthcare Materials, EarlyView.
Here persistent limitations in hemostatic technologies are highlighted and cutting‐edge biomimetic, microparticle‐assisted, and nanoengineered systems with integrated drug delivery are showcased. Moreover, the article identifies fresh directions toward the next‐generation of multifunctional hemostatic devices with superior efficacy and accessibility ...
Daniele Baiocco, Zhibing Zhang, Neil M. Eisenstein, Nigel Tai, Liam M. Grover   +4 more
wiley   +1 more source

Combination of convergence groups

, 2003
We state and prove a combination theorem for relatively hyperbolic groups seen as geometrically finite convergence groups. For that, we explain how to contruct a boundary for a group that is an acylindrical amalgamation of relatively hyperbolic groups ...
Bestvina, Bestvina, Bowditch, Dahmani, Francois Dahmani, Gehring, Gromov, Gromov, Hurewicz, Short, Tukia   +10 more
core   +3 more sources

AI‐Assisted Design and Evaluation of SLM‐Ti64 Implants for Enhanced Bone Regeneration

Advanced Healthcare Materials, EarlyView.
AI‐driven simulations of biological healing, combining biomechanical modeling and machine learning, enable personalized orthopedic treatments. By decoding healing patterns influenced by implants and patient‐specific factors, this approach advances fracture repair understanding, optimizes implant design, and supports precision medicine and sustainable ...
Muhammad Usama Zaheer, Muhammad Hassan Razzaq, Mehmet Fatih Aycan, Yogendra Kumar Mishra   +3 more
wiley   +1 more source

Computational Simulations of Metal–Organic Frameworks to Enhance Adsorption Applications

Advanced Materials, EarlyView.
This review highlights the significance of molecular simulations in expanding the understanding of metal–organic frameworks (MOFs) and improving their gas adsorption applications. The historical development and implementation of molecular simulations in the MOF field are given, high‐throughput computational screening studies used to unlock the ...
Hilal Daglar, Hasan Can Gulbalkan, Gokhan Onder Aksu, Seda Keskin   +3 more
wiley   +1 more source

A Perspective on Pathways Toward Commercial Sodium‐Ion Batteries

Advanced Materials, EarlyView.
Comprehensive analysis of the existing and prospective sodium‐ion battery (SIB) systems unveils that a wider application of SIBs should primarily focus on i) regulating the composition, morphology, surface chemistry, safety performance, and production feasibility of mainstream cathodes, ii) enhancing the high‐voltage stability, film formation ability ...
Zehao Cui, Chen Liu, Arumugam Manthiram
wiley   +1 more source

Design Strategies and Roles of Hydrogels for Sustainable Energy Conversion and Harvesting from Natural and Biological Environments

Advanced Materials, EarlyView.
This review examines hydrogel‐based technologies driven by environmental stimuli and emphasizes their unique contributions to energy conversion. It provides insights into design strategies and recent advancements in functional hydrogels, highlighting opportunities and challenges in this field.
Wanheng Lu, Wei Li Ong, Xinglong Pan, Zhiwei Li, Guo Tian, Ghim Wei Ho   +5 more
wiley   +1 more source