Results 111 to 120 of about 141,581 (359)
Suitability of post-Newtonian/numerical-relativity hybrid waveforms for gravitational wave detectors [PDF]
, 2011 Ilana MacDonald +2 more
openalex +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
The Qom school and a critique of religious pluralism with special reference to Ayatollah Javadi Amoli's philosophical analysis [PDF]
Kom: Časopis za Religijske Nauke, 2019 In the past few decades, the school in the historic city of Qom has played an important role in directing strategic scientific and cultural developments in Iran and the Islamic world. Scientific and research work in this school has been going on for more
Halilović Seid
doaj
GEODESIC MOTION IN GENERAL RELATIVITY: LARES IN EARTH'S GRAVITY [PDF]
, 2013 I. Ciufolini +3 more
openalex +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Reactionaries and Einstein’s Fame: “German Scientists for the Preservation of Pure Science,” Relativity, and the Bad Nauheim Meeting [PDF]
, 2007 Jeroen van Dongen
openalex +1 more source
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
This research answers the knowledge gap regarding the explanation of the quantum jump of the electron. This scientific paper aims to complete Einstein's research regarding general relativity and attempt to link general relativity to quantum laws.
Ahmed Mohamed Ismail +1 more
openaire +1 more source