Results 171 to 180 of about 86,860 (314)
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Black hole thermodynamics: general relativity and beyond
, 2019 Black holes have often provided profound insights into the nature of gravity and the structure of space–time. The study of the mathematical properties of black objects is a major research theme of contemporary theoretical physics.
Sarkar, Sudipta, Sudipta Sarkar
core +1 more source
Commentary: Physical time within human time
Frontiers in Psychology, 2023 Mark A. Elliott
doaj +1 more source
Black coffee. Marcel Duchamp’s pataphysical sensism
Relief: Revue Électronique de Littérature Francaise, 2016 Duchamp’s readymade is usually interpreted as a bold and cerebral emancipation of modern art from the material, the craft and natural beauty, and the discovery of the continent of conceptual art.
Dirk van Weelden
doaj
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Recent astronomical tests of general relativity
, 2015 The history of experimentation relevant to general relativity covers the time post-1928. Classes of investigation are the weak equivalence principle (equivalence of inertial and gravitational mass and gravitational redshift), orbital precession of a body
Treschman, Keith John
core +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Alternative conventions and geometry for special relativity [PDF]
, 2004 This paper argues that Einstein’s conventionalist definition of time is sufficient for, but not necessary to the geometric modelling of Special Relativity.
Crabbe, A
core
Relative Armut, relative Menschenwürde - relatives Desinteresse?
, 2010 Zu den Zielsetzungen politischer und ökonomischer Bildung werden politische und ökonomische Urteilsfähigkeit, Entscheidungsfähigkeit und Handlungsfähigkeit gerechnet. Der Essay ist zwei aktuellen Beispielen gewidmet, in denen mathematisch basierte Beurteilungs- und Entscheidungsgrundlagen Gegenstand der öffentlichen und medialen Auseinandersetzung ...
openaire +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source