Results 71 to 80 of about 4,314 (270)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Automated conceptual model clustering: a relator-centric approach. [PDF]
Softw Syst Model, 2022 Guizzardi G +3 more
europepmc +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Semantic interoperability: ontological unpacking of a viral conceptual model. [PDF]
BMC Bioinformatics, 2022 Bernasconi A +3 more
europepmc +1 more source
Tits alternatives for graph products
, 2015 We discuss various types of Tits Alternative for subgroups of graph products of groups, and prove that, under some natural conditions, a graph product of groups satisfies a given form of Tits Alternative if and only if each vertex group satisfies this ...
Antolin, Yago, Minasyan, Ashot
core +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
"First Catch Your Hare": Some Difficulties with, and Contextual Factors in, Understanding (In)Appropriate Workplace Relationships. [PDF]
Behav Sci (Basel), 2022 Duck S.
europepmc +1 more source
Order, 2010 There is a canonical way to associate two simplicial complexes K, L to any relation $R\subset X\times Y$. Moreover, the geometric realizations of K and L are homotopy equivalent. This was studied in the fifties by C.H. Dowker. In this article we prove a Galois-type correspondence for relations $R\subset X\times Y$ when X is fixed and use these ...
openaire +3 more sources
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Competences of the Congregation for the Causes of Saints
Kościół i Prawo, 2014 The article discusses the issue of the competences of the Congregation for the Causes of Saints. The Author begins with the origin of the Congregation. It is emphasized that this dicastery is one of the oldest organ of the Apostolic See.
Krzysztof Białowąs
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