Results 41 to 50 of about 1,057,083 (303)

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Rapid high resolution T1 mapping as a marker of brain development: Normative ranges in key regions of interest. [PDF]

PLoS ONE, 2018
ObjectivesWe studied in a clinical setting the age dependent T1 relaxation time as a marker of normal late brain maturation and compared it to conventional techniques, namely the apparent diffusion coefficient (ADC).Materials and methodsForty-two healthy
Sylvain Eminian, Steven David Hajdu, Reto Antoine Meuli, Philippe Maeder, Patric Hagmann   +4 more
doaj   +1 more source

Quasiparticle relaxation in optically excited high-Q superconducting resonators

, 2008
The quasiparticle relaxation time in superconducting films has been measured as a function of temperature using the response of the complex conductivity to photon flux.
J. J. A. Baselmans, J. N. Hovenier, J. R. Gao, M. Tinkham, R. Barends, S. J. C. Yates, T. M. Klapwijk   +6 more
core   +2 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Relaxation measurements in the regime of the second magnetization peak in Nb films

, 2004
We report on magnetic measurements as a function of field, temperature and time (relaxation) in superconducting Nb films of critical temperature Tc = 9.25 K.
Abulafia, Anderson, Anderson, Chowdhury, Chowdhury, D. Niarchos, D. Stamopoulos, Esquinazi, Finnemore, Giller, Giller, Gurevich, Janossy, Khaykovich, Kokkaliaris, Kopelevich, Kupfer, Mints, Mints, Miu, Pissas, Pissas, Stamopoulos, Stamopoulos, Stamopoulos, Stamopoulos, Sun, Sun, Swartz, Wipf, Wipf, Zhukov   +31 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Lower semicontinuity and relaxation of nonlocal $$L^\infty $$-functionals [PDF]

Calculus of Variations and Partial Differential Equations, 2020
AbstractWe study variational problems involving nonlocal supremal functionals$$\begin{aligned} L^\infty (\Omega ;{\mathbb {R}}^m) \ni u\mapsto \mathrm{ess sup}_{(x,y)\in \Omega \times \Omega } W(u(x), u(y)), \end{aligned}$$L∞(Ω;Rm)∋u↦esssup(x,y)∈Ω×ΩW(u(x),u(y)),where$$\Omega \subset \mathbb {R}^n$$Ω⊂Rnis a bounded, open set and$$W:\mathbb {R}^m\times ...
Carolin Kreisbeck, Elvira Zappale
openaire   +7 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Exponential decay of solutions to a fourth-order viscoelastic evolution equation in R^n

Electronic Journal of Differential Equations, 2010
In this article, we consider a Cauchy problem for a viscoelastic wave equation of fourth order. Under suitable conditions on the initial data and the relaxation function, we show that the rate of decay is exponential.
Mohammad Kafini
doaj  

Detecting impaired myocardial relaxation in sepsis with a novel tissue Doppler parameter (septal e′/s′)

Critical Care, 2017
Background Left ventricular diastolic dysfunction is associated with mortality outcomes in severe sepsis and septic shock. There are ongoing issues with diagnosing diastolic dysfunction in this cohort, partly owing to the poor applicability of ...
David J. Clancy, Michel Slama, Stephen Huang, Timothy Scully, Anthony S. McLean, Sam R. Orde   +5 more
doaj   +1 more source